Anti-Hepatitis B Virus Surface Antigen antibody [HB5] (ab8333)

Overview

  • Product nameAnti-Hepatitis B Virus Surface Antigen antibody [HB5]
    See all Hepatitis B Virus Surface Antigen primary antibodies
  • Description
    Mouse monoclonal [HB5] to Hepatitis B Virus Surface Antigen
  • SpecificityRecognizes following Hepatitis B virus subtypes:ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq- Specificity of MAb HB5 was verified by ELISA on panel of International Workshop on HBsAg Subtypes (Paris, April 1975). This antibody does not cross-block with ab8256 and is therefore suitable for use with ab8256 as a matched pair.
  • Tested applicationsSuitable for: ICC, ELISAmore details
  • Immunogen

    purified HbsAg from human plasma

Properties

Applications

Our Abpromise guarantee covers the use of ab8333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
  • Cellular localizationVirion membrane
  • Alternative names
    • Large envelope protein antibody
    • Large surface protein antibody
    • LHB antibody
    • Major surface antigen antibody

References for Anti-Hepatitis B Virus Surface Antigen antibody [HB5] (ab8333)

ab8333 has not yet been referenced specifically in any publications.

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We do offer a variety of antibodies that will recognize the four major serotypes: adr, adw, ayr, ayw.
If it has been tested which serotype is recognizwed by an antibody this information can be found on the datasheet ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"