Anti-Hepatitis C Virus antibody (ab1033)
Key features and details
- Rabbit polyclonal to Hepatitis C Virus
- Suitable for: WB
- Reacts with: Hepatitis C virus
- Isotype: unknown
Overview
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Product name
Anti-Hepatitis C Virus antibody
See all Hepatitis C Virus primary antibodies -
Description
Rabbit polyclonal to Hepatitis C Virus -
Host species
Rabbit -
Specificity
This antibody recognizes the core protein C1 of Hepatitis C Virus. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Hepatitis C virus -
Immunogen
Peptide corresponding to amino acids 9-21 of Hepatitis C Virus (HCV) core protein C1.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
unknown -
Light chain type
unknown -
Research areas
Associated products
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Compatible Secondaries
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab1033 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/1000.
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Notes |
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WB
1/500 - 1/1000. |
Target
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Relevance
Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. -
Cellular localization
Virus surface -
Database links
- Entrez Gene: 951475 Hepatitis C virus
- SwissProt: P27958 Hepatitis C virus
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Alternative names
- Genome polyprotein antibody
- HCV antibody
- Hepatitis C virus polyprotein antibody
Datasheets and documents
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SDS download
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Datasheet download
References (10)
ab1033 has been referenced in 10 publications.
- Pu A et al. The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination. J Neuroinflammation 17:220 (2020). PubMed: 32703234
- Aljowaie RM et al. Inhibition of hepatitis C virus genotype 4 replication using siRNA targeted to the viral core region and the CD81 cellular receptor. Cell Stress Chaperones 25:345-355 (2020). PubMed: 32060691
- Tessier S et al. TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression. Matrix Biol 87:94-111 (2020). PubMed: 31707045
- Hulin A et al. Maturation of heart valve cell populations during postnatal remodeling. Development 146:N/A (2019). PubMed: 30796046
- Mittal N et al. Versican is crucial for the initiation of cardiovascular lumen development in medaka (Oryzias latipes). Sci Rep 9:9475 (2019). PubMed: 31263118
- Joost S et al. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing. Cell Rep 25:585-597.e7 (2018). PubMed: 30332640
- Meier-Abt F et al. Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium. Breast Cancer Res 15:R36 (2013). IHC ; Mouse . PubMed: 23621987
- Hattori N et al. Pericellular versican regulates the fibroblast-myofibroblast transition: a role for ADAMTS5 protease-mediated proteolysis. J Biol Chem 286:34298-310 (2011). PubMed: 21828051
- Velasco J et al. Adamts5 deletion blocks murine dermal repair through CD44-mediated aggrecan accumulation and modulation of transforming growth factor ß1 (TGFß1) signaling. J Biol Chem 286:26016-27 (2011). PubMed: 21566131
- Yuk CS et al. Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus. Biotechnol Lett 26:1563-8 (2004). PubMed: 15604797