Anti-Hepatitis C Virus E1 antibody (ab110972)

Overview

  • Product nameAnti-Hepatitis C Virus E1 antibody
  • Description
    Goat polyclonal to Hepatitis C Virus E1
  • Tested applicationsSuitable for: ELISA, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Hepatitis C Virus
  • Immunogen

    Recombinant Hepatitis C Virus E1 (genotype 1a).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • PurityIon Exchange Chromatography
  • Purification notesab110972 is >95% pure by Sodium sulfate precipitation and ion exchange chromatography.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab110972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution. Reacts with genotype 1a.
WB Use at an assay dependent dilution. Predicted molecular weight: 23 kDa. Reacts with genotypes 1b and 2a.
ICC/IF Use at an assay dependent dilution. Reacts with genotype 1b, but does not react with genotype 2a.

Target

  • RelevanceEnvelope glycoproteins E1 and E2 are involved in virus attachment to the host cell as well as in virus endocytosis and fusion with host membrane. E2 inhibits human EIF2AK2/PKR activation, preventing the establishment of an antiviral state. E2 is a viral ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR, which are respectively found on dendritic cells (DCs), and on liver sinusoidal endothelial cells and macrophage-like cells of lymph node sinuses. These interactions allow capture of circulating HCV particles by these cells and subsequent transmission to permissive cells.
  • Database links
    • Alternative names
      • E1 envelope glycoprotein antibody
      • HCV envelope glycoprotein antibody
      • Hepatitis C Virus envelope glycoprotein antibody

    References for Anti-Hepatitis C Virus E1 antibody (ab110972)

    ab110972 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab110972.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"