Anti-Hepatitis C Virus genotype 5 NS5 antibody (ab89617)

Overview

  • Product nameAnti-Hepatitis C Virus genotype 5 NS5 antibody
  • Description
    Rabbit polyclonal to Hepatitis C Virus genotype 5 NS5
  • SpecificityDetects genotype NS5a, 2A, JFH-1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with HCV
  • Immunogen

    HCV NS5a

Properties

Applications

Our Abpromise guarantee covers the use of ab89617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1 - 1/1000.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceHepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008). NS5B (non-structural protein 5B) is an RNA-dependant RNA polymerase responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication. Hepatitis C virus (HCV) can cause chronic hepatitis, cirrhosis and hepatocellular carcinoma. At present there is no vaccine effective against HCV.
  • Cellular localizationEndoplasmic reticulum membrane
  • Alternative names
    • HCV NS5A antibody
    • HCV NS5 antibody
    • Hepatitis C virus NS5A antibody
    • Non structural protein 5A antibody
    • p56 antibody
    see all

References for Anti-Hepatitis C Virus genotype 5 NS5 antibody (ab89617)

ab89617 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89617.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"