Anti-Hepatitis C Virus NS4A antibody [S4-13] (FITC) (ab124528)

Overview

  • Product nameAnti-Hepatitis C Virus NS4A antibody [S4-13] (FITC)
    See all Hepatitis C Virus NS4A primary antibodies
  • Description
    Mouse monoclonal [S4-13] to Hepatitis C Virus NS4A (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Hepatitis C Virus
  • Immunogen

    Recombinant fragment corresponding to Hepatitis C Virus Hepatitis C Virus NS4A.

  • EpitopeThe epitope of this antibody was mapped to the N terminal region of the NS4 protein (NS4A).
  • Positive control
    • Chimp liver cells infected with recombinant vaccinia virus containing a Hepatitis C Virus genome cDNA.
  • General notes

    [FITC] / [IgG] = 10.4

Properties

Applications

Our Abpromise guarantee covers the use of ab124528 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 6 kDa.
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

Target

  • RelevanceHepatitis C Virus is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of Hepatitis C Virus with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha
  • Cellular localizationHost endoplasmic reticulum membrane; Single-pass type I membrane protein Potential. Note: Host membrane insertion occurs after processing by the NS3 protease.
  • Database links
    • Alternative names
      • core protein antibody
      • E1 protein antibody
      • E2 protein antibody
      • HCV NS4A antibody
      • Non structural protein 4A antibody
      • NS2 protein antibody
      • NS3 protease/helicase antibody
      • NS4A antibody
      • NS4A protein antibody
      • NS4B protein antibody
      • NS5A protein antibody
      • NS5B RNA-dependent RNA polymerase antibody
      • p7 protein antibody
      • polyprotein antibody
      see all

    References for Anti-Hepatitis C Virus NS4A antibody [S4-13] (FITC) (ab124528)

    ab124528 has not yet been referenced specifically in any publications.

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