Anti-HePTP / PTPN7 antibody [AFPK32] (ab75523)

Overview

  • Product nameAnti-HePTP / PTPN7 antibody [AFPK32]
    See all HePTP / PTPN7 primary antibodies
  • Description
    Mouse monoclonal [AFPK32] to HePTP / PTPN7
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length Human HePTP/ PTPN7 protein purified from E. coli

  • Positive control
    • Bosc23 cell lysate transfected with Myc/His/HePTP / PTPN7.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.03% Sodium Azide
    Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride
  • Concentration information loading...
  • PurityAmmonium Sulphate Precipitation
  • ClonalityMonoclonal
  • Clone numberAFPK32
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab75523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Predicted molecular weight: 40 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionProtein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
  • Tissue specificityExpressed exclusively in thymus and spleen.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Post-translational
    modifications
    Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • BPTP 4 antibody
    • BPTP4 antibody
    • Dual specificity phosphatase 1 antibody
    • Hematopoietic protein tyrosine phosphatase antibody
    • Hematopoietic protein-tyrosine phosphatase antibody
    • HEPTP antibody
    • LC PTP antibody
    • LCPTP antibody
    • LPTP antibody
    • Protein tyrosine phoshatase non receptor type stress induced antibody
    • Protein tyrosine phoshatase nonreceptor type stress induced antibody
    • Protein tyrosine phosphatase LC PTP antibody
    • Protein tyrosine phosphatase non receptor type 7 antibody
    • Protein-tyrosine phosphatase LC-PTP antibody
    • PTN7_HUMAN antibody
    • PTPN 7 antibody
    • Ptpn7 antibody
    • PTPNI antibody
    • Tyrosine protein phosphatase non receptor type 7 antibody
    • Tyrosine-protein phosphatase non-receptor type 7 antibody
    see all

References for Anti-HePTP / PTPN7 antibody [AFPK32] (ab75523)

ab75523 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"