Anti-HERPUD1 antibody (ab155778)
Key features and details
- Rabbit polyclonal to HERPUD1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-HERPUD1 antibody
See all HERPUD1 primary antibodies -
Description
Rabbit polyclonal to HERPUD1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 9-251 of Human HERPUD1 (Q15011).
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Positive control
- 293T and Mouse brain whole cell lysate; Human U251 xenograft tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab155778 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 44 kDa.
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IHC-P |
1/100 - 1/1000.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 44 kDa. |
IHC-P
1/100 - 1/1000. |
Target
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Function
Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation. -
Tissue specificity
Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease. -
Sequence similarities
Contains 1 ubiquitin-like domain. -
Cellular localization
Endoplasmic reticulum membrane. - Information by UniProt
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Database links
- Entrez Gene: 9709 Human
- Entrez Gene: 64209 Mouse
- Omim: 608070 Human
- SwissProt: Q15011 Human
- SwissProt: Q9JJK5 Mouse
- Unigene: 146393 Human
- Unigene: 29151 Mouse
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Alternative names
- HERP antibody
- HERP1_HUMAN antibody
- HERPUD1 antibody
see all
Images
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Anti-HERPUD1 antibody (ab155778) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg
Predicted band size: 44 kDa
10% SDS PAGE -
Anti-HERPUD1 antibody (ab155778) at 1/5000 dilution + 293T whole cell lysate at 30 µg
Predicted band size: 44 kDa
7.5% SDS PAGE -
Immunohistochemical analysis of paraffin-embedded Human U251 xenograft tissue, labeling HERPUD1 with ab155778 at 1/500 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab155778 has been referenced in 1 publication.
- Villar VH et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun 8:14124 (2017). PubMed: 28112156