Overview

  • Product nameAnti-HES5 antibody
    See all HES5 primary antibodies
  • Description
    Rabbit polyclonal to HES5
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to a region within N terminal amino acids 1-50 of Human HES5 (Q5TA89)

  • Positive control
    • Mouse liver tissue lysate and Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab107593 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 6 - 9 µg/ml. Predicted molecular weight: 18 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionTranscriptional repressor of genes that require a bHLH protein for their transcription.
  • Tissue specificityExpressed in fetal heart and brain tumors.
  • Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
    Contains 1 Orange domain.
  • DomainHas a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
    The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • bHLHb38 antibody
    • Class B basic helix-loop-helix protein 38 antibody
    • Hairy and enhancer of split 5 antibody
    • Hairy/Enhancer of spli, Drosophila, homolog of, 5 antibody
    • HES 5 antibody
    • hes family bHLH transcription factor 5 antibody
    • Hes5 antibody
    • HES5 protein antibody
    • HES5_HUMAN antibody
    • MGI:104876 antibody
    • Transcription factor HES-5 antibody
    see all

Anti-HES5 antibody images

  • All lanes : Anti-HES5 antibody (ab107593) at 7 µg/ml

    Lane 1 : HES5 in mouse liver tissue
    Lane 2 : HES5 in mouse liver tissue with immunizing peptide

    Secondary
    Goat anti-rabbit Ig HRP
    Developed using the ECL technique

    Predicted band size : 18 kDa
  • Immunohistochemical analysis of HES5 in formalin-fixed, paraffin-embedded human brain tissue using ab107593 at 5 µg/ml.

References for Anti-HES5 antibody (ab107593)

ab107593 has not yet been referenced specifically in any publications.

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