Overview

  • Product nameAnti-HES6 antibody
    See all HES6 primary antibodies
  • Description
    Rabbit polyclonal to HES6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide designed between amino acids 13~42 from the N-terminal region of Human HES6.

  • Positive control
    • MCF7 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab102823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 24 kDa.

Target

  • RelevanceHES6 is a transcription cofactor that iteself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumour and cancer cell lines, although these have not yet been elucidated fully.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • bHLHb41 antibody
    • bHLHc23 antibody
    • C HAIRY1 antibody
    • Class B basic helix-loop-helix protein 41 antibody
    • Hairy and enhancer of split 6 antibody
    • HES 6 antibody
    • Transcription cofactor HES6 antibody
    see all

Anti-HES6 antibody images

  • Anti-HES6 antibody (ab102823) at 1/100 dilution + MCF7 cell line lysate at 35 µg

    Predicted band size : 24 kDa

References for Anti-HES6 antibody (ab102823)

ab102823 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"