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Product name Anti-HES6 antibody See all HES6 primary antibodies
Rabbit polyclonal to HES6
Synthetic peptide conjugated to KLH derived from within residues 200 to the C-terminus of Human HES6.
(Peptide available as
This antibody gave a positive signal in the following whole cell lysates: HeLa; Jurkat; HepG2; HEK293; A549; Raji; SHSY5Y.
Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Relevance HES6 is a transcription cofactor that iteself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence.
HES6 appears to have novel functions in tumour and cancer cell lines, although these have not yet been elucidated fully.
Cellular localization Nuclear
C HAIRY1 antibody
Anti-HES6 antibody images
This Fast-Track antibody is not yet fully characterised. These images represent
inconclusive preliminary data.
Western blot - HES6 antibody (ab76982)
All lanes : Anti-HES6 antibody (ab76982) at 1 µg/ml Lane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 5 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell Lysate Lane 6 : Raji (Human Burkitt's lymphoma cell line) Whole Cell Lysate Lane 7 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane. Secondary Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution developed using the ECL technique Performed under reducing conditions. Observed band size : 38 kDa ( why is the actual band size different from the predicted?) Exposure time : 20 minutes
References for Anti-HES6 antibody (ab76982)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"