• Product name
  • Description
    Rabbit polyclonal to HES7
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide derived from a region between residues 62-112 of human HES7.


  • Positive control
    • Fetal human heart lysate, Human kidney and human pancreas tissue.



Our Abpromise guarantee covers the use of ab26062 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use at an assay dependent concentration.


  • Function
    Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.
  • Involvement in disease
    Defects in HES7 are the cause of spondylocostal dysostosis type 4 (SCDO4) [MIM:613686]. A rare condition of variable severity characterized by vertebral and costal anomalies. The main feature include dwarfism, vertebral fusion, hemivertebrae, posterior rib fusion, reduced rib number, and other rib malformations.
  • Sequence similarities
    Contains 1 basic helix-loop-helix (bHLH) domain.
    Contains 1 Orange domain.
  • Domain
    Has a particular type of basic domain which includes a helix-interrupting proline.
    The C-terminal WRPW motif is a transcriptional repression motif which is necessary for interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • bHLH factor Hes7 antibody
    • bHLHb37 antibody
    • Class B basic helix loop helix protein 37 antibody
    • Class B basic helix-loop-helix protein 37 antibody
    • Hairy and enhancer of split 7 antibody
    • hes family bHLH transcription factor 7 antibody
    • Hes7 antibody
    • HES7_HUMAN antibody
    • hHes7 antibody
    • SCDO4 antibody
    • Transcription factor HES 7 antibody
    • Transcription factor HES-7 antibody
    see all

Anti-HES7 antibody images

  • Anti-HES7 antibody (ab26062) at 1 µg/ml (in 5% skim milk / PBS buffer) + fetal human heart lysate

    HRP conjugated anti-Rabbit IgG

    Predicted band size : 25 kDa
    Observed band size : 25,26 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemical detection of HES7 using 4 ug/ml ab26062 in paraffin embedded human kidney tissue section. Arrows indicate positively labelled epithelial cells of the renal tubule.
  • Immunohistochemical detection of HES7 using 4 ug/ml ab26062 in paraffin embedded human pancreas tissue section. Arrows indicate positively labelled epithelial cells of the pancreatic acinus.

References for Anti-HES7 antibody (ab26062)

ab26062 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry.

According to the SwissProt home page (http://www.uniprot.org/uniprot/Q9BYE0) there is only one isoform.

Since I ma not experienced in the field of Transcription factor HES-7 I can only confirm that if bot...

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Thank you for your inquiry.

The exact immunogen sequences for these two antibodies are proprietary information. All the information I can provide is the region as it is stated on the datasheets:

ab26062: The immunogen is within ther...

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