Overview

  • Product name
  • Description
    Rabbit polyclonal to HEXIM1
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 1-50 of Human HEXIM1 (NP_006451.1).

  • Positive control
    • HeLa whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab112094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
    • Tissue specificity
      Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues.
    • Sequence similarities
      Belongs to the HEXIM family.
    • Domain
      The coiled-coil domain mediates oligomerization.
    • Cellular localization
      Nucleus. Cytoplasm. Binds alpha-importin and is mostly nuclear.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cardiac lineage protein 1 antibody
      • CLP 1 antibody
      • CLP1 antibody
      • EDG 1 antibody
      • EDG1 antibody
      • Estrogen down-regulated gene 1 protein antibody
      • FLJ13562 antibody
      • Hexamethylene bis acetamide inducible 1 antibody
      • Hexamethylene bis acetamide inducible protein antibody
      • Hexamethylene bis acetamide inducible transcript 1 antibody
      • Hexamethylene bis-acetamide-inducible protein 1 antibody
      • HEXI1_HUMAN antibody
      • HEXIM 1 antibody
      • Hexim1 antibody
      • HEXIM1 protein antibody
      • HIS 1 antibody
      • HIS1 antibody
      • HMBA inducible antibody
      • MAQ 1 antibody
      • MAQ1 antibody
      • Menage a quatre 1 antibody
      • Menage a quatre protein 1 antibody
      • Protein HEXIM1 antibody
      see all

    References

    ab112094 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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