Overview

  • Product name
  • Description
    Rabbit polyclonal to HEXIM2
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 1-50 of Human HEXIM2 (NP_653209.1)

  • Positive control
    • HeLa whole cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.50
    Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: 7 to 8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab112041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
    • Tissue specificity
      Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
    • Sequence similarities
      Belongs to the HEXIM family.
    • Domain
      The coiled-coil domain mediates oligomerization.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Hexamethylene bis-acetamide-inducible protein 2 antibody
      • Hexamthylene bis-acetamide inducible 2 antibody
      • HEXI2_HUMAN antibody
      • hexim 2 antibody
      • HEXIM2 antibody
      • L3 antibody
      • Protein HEXIM2 antibody
      see all

    Images

    • Detection of HEXIM2 by Western Blot of Immunprecipitate.
      ab112041 at 1µg/ml staining HEXIM2 in HeLa whole cell lysate immunoprecipitated using ab112041 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.

    References

    ab112041 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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