Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab46528 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 µg/ml. Predicted molecular weight: 32 kDa.
ELISA Use at an assay dependent dilution.

Target

  • Function
    Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
  • Tissue specificity
    Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
  • Sequence similarities
    Belongs to the HEXIM family.
  • Domain
    The coiled-coil domain mediates oligomerization.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Hexamethylene bis-acetamide-inducible protein 2 antibody
    • Hexamthylene bis-acetamide inducible 2 antibody
    • HEXI2_HUMAN antibody
    • hexim 2 antibody
    • HEXIM2 antibody
    • L3 antibody
    • Protein HEXIM2 antibody
    see all

Images

  • All lanes : Anti-HEXIM2 antibody (ab46528)

    Lane 1 : U373 cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : 293T cell lysate
    Lane 4 : SK-Hep-1 cell lysate
    Lane 5 : IMR-90 cell lysate
    Lane 6 : TK6 cell lysate
    Lane 7 : CaCo-2 cell lysate


    Predicted band size : 32 kDa
    Observed band size : 32 kDa

References

ab46528 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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