Recombinant
RabMAb

Anti-Hexokinase 1 antibody [EPR10135(B)] (ab154839)

Overview

  • Product name
    Anti-Hexokinase 1 antibody [EPR10135(B)]
    See all Hexokinase 1 primary antibodies
  • Description
    Rabbit monoclonal [EPR10135(B)] to Hexokinase 1
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Hexokinase 1 (Uniprot: P19367)

  • Positive control
    • 293T, MCF7, U-87 MG and HeLa cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab154839 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 102 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Tissue specificity
      Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.
    • Pathway
      Carbohydrate metabolism; hexose metabolism.
    • Involvement in disease
      Hexokinase deficiency
      Neuropathy, hereditary motor and sensory, Russe type
    • Sequence similarities
      Belongs to the hexokinase family.
      Contains 2 hexokinase domains.
    • Domain
      The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule.
    • Cellular localization
      Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
    • Information by UniProt
    • Database links
    • Alternative names
      • BB404130 antibody
      • Brain form hexokinase antibody
      • dea antibody
      • DrHXK1 antibody
      • EC 2.7.1.1 antibody
      • Glycolytic enzyme antibody
      • HEXOKIN antibody
      • hexokinase I antibody
      • Hexokinase PI antibody
      • Hexokinase type I antibody
      • Hexokinase, tumor isozyme antibody
      • Hexokinase-1 antibody
      • Hexokinase-A antibody
      • HK I antibody
      • HK1 antibody
      • HK1 tb antibody
      • Hk1-s antibody
      • HK1-ta antibody
      • HK1-tb antibody
      • HK1-tc antibody
      • HKD antibody
      • HKI antibody
      • HMSNR antibody
      • HXK1 antibody
      • HXK1_HUMAN antibody
      • im:7148527 antibody
      • mHk1-s antibody
      • wu:fc09d08 antibody
      • wu:fc16e02 antibody
      • wu:fc21e02 antibody
      • wu:fq14b11 antibody
      • zgc:55790 antibody
      • zgc:77618 antibody
      see all

    Images

    • All lanes : Anti-Hexokinase 1 antibody [EPR10135(B)] (ab154839) at 1/1000 dilution

      Lane 1 : 293T cell lysate
      Lane 2 : MCF7 cell lysate
      Lane 3 : U-87 MG cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 102 kDa

    References

    ab154839 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab154839.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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