Overview

  • Product nameAnti-HGD antibody
    See all HGD primary antibodies
  • Description
    Mouse polyclonal to HGD
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length HGD protein (Human) (AAH71757.1)

  • Positive control
    • HGD transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab70084 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).

Target

  • Tissue specificityHighest expression in the prostate, small intestine, colon, kidney and liver.
  • PathwayAmino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.
  • Involvement in diseaseDefects in HGD are the cause of alkaptonuria (AKU) [MIM:203500]. AKU is an autosomal recessive error of metabolism characterized by an increase in the level of homogentisic acid. The clinical manifestations of AKU are urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues, and spine arthritis.
  • Sequence similaritiesBelongs to the homogentisate dioxygenase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2-dioxygenase antibody
    • AKU antibody
    • FLJ94126 antibody
    • hgd antibody
    • HGD_HUMAN antibody
    • HGO antibody
    • Homogentisate 1 2 dioxygenase antibody
    • Homogentisate 1 antibody
    • Homogentisate oxidase antibody
    • Homogentisate oxygenase antibody
    • Homogentisic acid oxidase antibody
    • Homogentisicase antibody
    see all

Anti-HGD antibody images

  • All lanes : Anti-HGD antibody (ab70084) at 1/500 dilution

    Lane 1 : HGD transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 50 kDa
    Observed band size : 50 kDa

References for Anti-HGD antibody (ab70084)

ab70084 has not yet been referenced specifically in any publications.

Product Wall

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