The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: Use at an assay dependant dilution.
IP: Use Protein A; 2 µg/mg of protein lysate.
WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 82 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionPotent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
Involvement in diseaseDeafness, autosomal recessive, 39
Sequence similaritiesBelongs to the peptidase S1 family. Plasminogen subfamily. Contains 4 kringle domains. Contains 1 PAN domain. Contains 1 peptidase S1 domain.
References for Anti-HGF antibody [0.N.326] (ab4260)
This product has been referenced in:
Salehi Z & Rajaei F Expression of hepatocyte growth factor in the serum and cerebrospinal fluid of patients with Parkinson's disease. J Clin Neurosci : (2010).
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