Anti-HGFA Inhibitor 2 antibody [MM0323-3S24] (ab89238)

Overview

  • Product name
    Anti-HGFA Inhibitor 2 antibody [MM0323-3S24]
    See all HGFA Inhibitor 2 primary antibodies
  • Description
    Mouse monoclonal [MM0323-3S24] to HGFA Inhibitor 2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to the extracelluler domain of Human HGFA Inhibitor 2.

Properties

Applications

Our Abpromise guarantee covers the use of ab89238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 28 kDa.

Target

  • Function
    Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.
  • Tissue specificity
    Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.
  • Involvement in disease
    Defects in SPINT2 are the cause of diarrhea type 3 (DIAR3) [MIM:270420]; also known as congenital sodium diarrhea (CSD). DIAR3 is a rare, inherited diarrhea of infancy. A diagnosis of DIAR3 is made on the findings of a life-threatening secretory diarrhea, severe metabolic acidosis, and hyponatremia secondary to extraordinarily high fecal losses of sodium, with low or normal excretion of urinary sodium, in the absence of infectious, autoimmune, and endocrine causes.
  • Sequence similarities
    Contains 2 BPTI/Kunitz inhibitor domains.
  • Domain
    This inhibitor contains two inhibitory domains.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AL024025 antibody
    • Bikunin, placental antibody
    • C76321 antibody
    • DIAR3 antibody
    • FLJ45571 antibody
    • HAI-2 antibody
    • HAI2 antibody
    • Hepatocyte growth factor activator inhibitor type 2 antibody
    • Kop antibody
    • Kunitz type protease inhibitor 2 antibody
    • Kunitz-type protease inhibitor 2 antibody
    • Kunitz-type serine protease inhibitor antibody
    • MGC72638 antibody
    • PB antibody
    • Placental bikunin antibody
    • Serine peptidase inhibitor Kunitz type 2 antibody
    • Serine protease inhibitor, Kunitz type, 2 antibody
    • SPINT2 antibody
    • SPIT2_HUMAN antibody
    see all

References

ab89238 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab89238.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up