Anti-HGFA Inhibitor 2 antibody [RM0089-7F52] (ab86449)

Overview

  • Product nameAnti-HGFA Inhibitor 2 antibody [RM0089-7F52]
    See all HGFA Inhibitor 2 primary antibodies
  • Description
    Rat monoclonal [RM0089-7F52] to HGFA Inhibitor 2
  • SpecificityDoes not bind to HGFA Inhibitor 1. Recognizes all three Mouse isoforms.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant fragment corresponding to the extracellular region of Mouse HGFA Inhibitor 2

Properties

Applications

Our Abpromise guarantee covers the use of ab86449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Predicted molecular weight: 28 kDa (isoform 1).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.
    • Tissue specificityExpressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.
    • Involvement in diseaseDefects in SPINT2 are the cause of diarrhea type 3 (DIAR3) [MIM:270420]; also known as congenital sodium diarrhea (CSD). DIAR3 is a rare, inherited diarrhea of infancy. A diagnosis of DIAR3 is made on the findings of a life-threatening secretory diarrhea, severe metabolic acidosis, and hyponatremia secondary to extraordinarily high fecal losses of sodium, with low or normal excretion of urinary sodium, in the absence of infectious, autoimmune, and endocrine causes.
    • Sequence similaritiesContains 2 BPTI/Kunitz inhibitor domains.
    • DomainThis inhibitor contains two inhibitory domains.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AL024025 antibody
      • Bikunin, placental antibody
      • C76321 antibody
      • DIAR3 antibody
      • FLJ45571 antibody
      • HAI-2 antibody
      • HAI2 antibody
      • Hepatocyte growth factor activator inhibitor type 2 antibody
      • Kop antibody
      • Kunitz type protease inhibitor 2 antibody
      • Kunitz-type protease inhibitor 2 antibody
      • Kunitz-type serine protease inhibitor antibody
      • MGC72638 antibody
      • PB antibody
      • Placental bikunin antibody
      • Serine peptidase inhibitor Kunitz type 2 antibody
      • Serine protease inhibitor, Kunitz type, 2 antibody
      • SPINT2 antibody
      • SPIT2_HUMAN antibody
      see all

    References for Anti-HGFA Inhibitor 2 antibody [RM0089-7F52] (ab86449)

    ab86449 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"