Overview

  • Product name
  • Description
    Rabbit polyclonal to Hhip
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment containing a sequence corresponding to a region within amino acids 386-595 of Human Hhip (UniProt: Q96QV1)

  • Positive control
    • NT2D1 whole cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 20% Glycerol, 1.21% Tris
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126147 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 79 kDa.

Target

  • Function
    Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.
  • Tissue specificity
    Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney.
  • Sequence similarities
    Belongs to the HHIP family.
    Contains 2 EGF-like domains.
  • Domain
    A flexible loop interacts with the SHH zinc binding site and contributes to zinc binding.
  • Cellular localization
    Cytoplasm and Cell membrane. Secreted. The last 22 C-terminal amino acids may participate in cell membrane attachment.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ20992 antibody
    • FLJ90230 antibody
    • Hedgehog interacting protein antibody
    • Hedgehog-interacting protein antibody
    • hedgehoginteracting protein antibody
    • HHIP antibody
    • HHIP_HUMAN antibody
    • Hip antibody
    see all

Images

  • Anti-Hhip antibody (ab126147) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

    Predicted band size: 79 kDa



    7.5% SDS PAGE

References

ab126147 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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