Overview

  • Product name
    Anti-Hhip antibody [RM0090-8L46]
    See all Hhip primary antibodies
  • Description
    Rat monoclonal [RM0090-8L46] to Hhip
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant fragment corresponding to the extracellular domain of mouse Hhip.

Properties

  • Form
    Lyophilised:Reconstitute the antibody with 200µl sterile PBS for an 0.5mg/ml solution.
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from an 0.2 µm filtered solution.
  • Clonality
    Monoclonal
  • Clone number
    RM0090-8L46
  • Isotype
    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab86450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.

Target

  • Function
    Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.
  • Tissue specificity
    Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney.
  • Sequence similarities
    Belongs to the HHIP family.
    Contains 2 EGF-like domains.
  • Domain
    A flexible loop interacts with the SHH zinc binding site and contributes to zinc binding.
  • Cellular localization
    Cytoplasm and Cell membrane. Secreted. The last 22 C-terminal amino acids may participate in cell membrane attachment.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ20992 antibody
    • FLJ90230 antibody
    • Hedgehog interacting protein antibody
    • Hedgehog-interacting protein antibody
    • hedgehoginteracting protein antibody
    • HHIP antibody
    • HHIP_HUMAN antibody
    • Hip antibody
    see all

References

ab86450 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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