Overview

  • Product nameAnti-HHV8 Cyclin antibody [94B]
  • Description
    Rat monoclonal [94B] to HHV8 Cyclin
  • Tested applicationsSuitable for: IP, WB, ICC/IFmore details
  • Species reactivity
    Reacts with HHV8-encoded D type cyclin.
  • Immunogen

    Recombinant fusion protein produced from a clone from HHV8.

Properties

Applications

Our Abpromise guarantee covers the use of ab12208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 30 kDa.
ICC/IF Use at an assay dependent dilution.

Target

  • RelevanceHHV8 is associated with the develpment of Kaposi's Sarcoma and a number of B cell lymphomas in AIDS patients. HHV8 encodes a viral (v) cyclin homologous to cellular D type cyclins, a class of positive cell cycle regulators that are physiologically modulated by the p27(Kip1) cell cycle inhibitor.
  • Alternative names
    • HHV 8 cyclin antibody
    • HHV 8c antibody
    • Human Herpesvirus 8 ORF72 antibody
    • Kaposi's sarcoma associated herpesvirus antibody
    • KSHV ORF72 antibody
    • ORF 72 antibody
    see all

References for Anti-HHV8 Cyclin antibody [94B] (ab12208)

This product has been referenced in:
  • Sharma-Walia N  et al. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol 88:2131-56 (2014). Read more (PubMed: 24335295) »
  • Sin SH & Dittmer DP Viral latency locus augments B-cell response in vivo to induce chronic marginal zone enlargement, plasma cell hyperplasia, and lymphoma. Blood 121:2952-63 (2013). Read more (PubMed: 23365457) »

See all 3 Publications for this product

Product Wall



Unfortunately, we do not have any information on this particular query.
We would suggest that publication related to this antibody may give some information but we do not know that there is anything specific.

Thank you for your telephone enquiry yesterday afternoon. As requested, here is a list of all our antibodies for detection of HHV8 virus. I can recommend to review the online datasheets for further information. ab4103 Rat monoclonal Anti...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"