Overview

  • Product nameAnti-HHV8 GPCR antibody
  • Description
    Rabbit polyclonal to HHV8 GPCR
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Cross-reacts with Human Herpesvirus 8
  • Immunogen

    E-coli expressed recombinant fragment, corresponding to N terminal amino acids 1-41 of HHV8 GPCR

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab25122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • RelevanceKaposi's sarcoma-associated herpesvirus (KSHV, or human herpesvirus 8, HHV8), is a gamma herpesvirus that contain an open reading frame encoding a G protein-coupled receptor (GPCR) with putative 7 transmembrane domains. This GPCR has been shown to bind a number of chemokines including IL8, NAP2, PF4, MGSA/Gro alpha, I309, RANTES, MCP1, and MIP1 beta. The receptor is constitutively activated without chemokine binding, and it stimulates cell proliferation. KSHV GPCR is also a viral oncogene that stimulates angio-genesis through induction of VEGF expression. IP10, a chemokine, can inhibit constitutively activated KSHV GPCR.
  • Alternative names
    • Human Herpesvirus 8 GPCR antibody
    • Kaposi's sarcoma-associated herpesvirus GPCR antibody
    • KSHV GPCR antibody

References for Anti-HHV8 GPCR antibody (ab25122)

ab25122 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your telephone enquiry yesterday afternoon. As requested, here is a list of all our antibodies for detection of HHV8 virus. I can recommend to review the online datasheets for further information. ab4103 Rat monoclonal Anti...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"