Anti-HIF-1 alpha antibody - ChIP Grade (ab2185)

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ab2185 has been referenced in 36 publications.

  • Shi W  et al. Transplantation of RADA16-BDNF peptide scaffold with human umbilical cord mesenchymal stem cells forced with CXCR4 and activated astrocytes for repair of traumatic brain injury. Acta Biomater 45:247-261 (2016). WB ; Rat . PubMed: 27592818
  • Chen Y  et al. MicroRNA-18b inhibits the growth of malignant melanoma via inhibition of HIF-1a-mediated glycolysis. Oncol Rep 36:471-9 (2016). WB . PubMed: 27220837
  • Chourasia AH  et al. Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis. EMBO Rep 16:1145-63 (2015). WB, IHC ; Mouse . PubMed: 26232272
  • Zheng X  et al. Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response. Proc Natl Acad Sci U S A 111:2560-5 (2014). ChIP . PubMed: 24550283
  • Cheverud JM  et al. Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. Heredity (Edinb) 112:508-18 (2014). Mouse . PubMed: 24569637
  • Aesoy R  et al. Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways. Mol Cancer 13:54 (2014). WB ; Human . PubMed: 24618291
  • Storti F  et al. A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression. Haematologica 99:e45-8 (2014). ChIP . PubMed: 24510339
  • Asnaghi L  et al. Hypoxia Promotes Uveal Melanoma Invasion through Enhanced Notch and MAPK Activation. PLoS One 9:e105372 (2014). IHC-Fr ; Human . PubMed: 25166211
  • Paatero I  et al. Hypoxia-inducible factor-1a induces ErbB4 signaling in the differentiating mammary gland. J Biol Chem 289:22459-69 (2014). WB ; Mouse . PubMed: 24966332
  • Vavilala DT  et al. Evaluation of anti-HIF and anti-angiogenic properties of honokiol for the treatment of ocular neovascular diseases. PLoS One 9:e113717 (2014). WB, ChIP ; Human . PubMed: 25422886
  • Chen X  et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1a pathway. Nature 508:103-7 (2014). ChIP ; Human . PubMed: 24670641
  • Biswas S  et al. Insulin regulates hypoxia-inducible factor-1a transcription by reactive oxygen species sensitive activation of Sp1 in 3T3-L1 preadipocyte. PLoS One 8:e62128 (2013). WB ; Mouse . PubMed: 23626778
  • Yi T  et al. Hypoxia-inducible factor-1a (HIF-1a) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions. J Biol Chem 288:18732-42 (2013). ChIP ; Human . PubMed: 23667251
  • Xin X  et al. Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4. Proc Natl Acad Sci U S A 110:E3425-34 (2013). WB ; Mouse . PubMed: 23959876
  • Ronkainen VP  et al. Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling. Cardiovasc Res N/A:N/A (2013). PubMed: 24095869
  • Weijts BG  et al. E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. EMBO J 31:3871-84 (2012). ChIP . PubMed: 22903062
  • Doublier S  et al. HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast. BMC Cancer 12:4 (2012). IHC-P ; Human . PubMed: 22217342
  • Zhou W  et al. HIF1a induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition. EMBO J : (2012). WB ; Mouse . PubMed: 22446391
  • Hari Kishore A  et al. Hypoxia and PGE(2) regulate MiTF-CX during cervical ripening. Mol Endocrinol 26:2031-45 (2012). PubMed: 23144021
  • Stiehl DP  et al. Non-canonical HIF-2a function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop. Oncogene 31:2283-97 (2012). PubMed: 21927022
  • Wollenick K  et al. Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. Nucleic Acids Res 40:1928-43 (2012). ChIP . PubMed: 22075993
  • Hu J  et al. Interaction of HIF and USF signaling pathways in human genes flanked by hypoxia-response elements and E-box palindromes. Mol Cancer Res 9:1520-36 (2011). ChIP ; Human . PubMed: 21984181
  • Jensen KS  et al. FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function. EMBO J 30:4554-70 (2011). ChIP . PubMed: 21915097
  • Gaber T  et al. Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1alpha function and differentially influences human CD4+ T cell proliferation under hypoxia. J Immunol 186:764-74 (2011). ChIP ; Human . PubMed: 21169549
  • Vanhorebeek I  et al. Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab 96:E633-45 (2011). WB ; Human . PubMed: 21270330
  • Ortiz-Barahona A  et al. Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Nucleic Acids Res : (2010). ChIP ; Human . PubMed: 20061373
  • Pescador N  et al. Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1. PLoS One 5:e9644 (2010). ChIP ; Mouse . PubMed: 20300197
  • Acosta-Iborra B  et al. Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1alpha transcription factor. J Immunol 182:3155-64 (2009). ChIP ; Mouse . PubMed: 19234213
  • Piña-Oviedo S  et al. Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol 118:235-47 (2009). ChIP ; Human . PubMed: 19360424
  • Zhang Z  et al. MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT. Cell Cycle 8:2756-68 (2009). ChIP ; Human . PubMed: 19652553
  • Beyer S  et al. The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. J Biol Chem 283:36542-52 (2008). ChIP ; Human . PubMed: 18984585
  • Sahlgren C  et al. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci U S A 105:6392-7 (2008). ChIP ; Human . PubMed: 18427106
  • Belaidi E  et al. Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat. Am J Physiol Heart Circ Physiol 294:H901-8 (2008). ChIP ; Rat . PubMed: 18083903
  • Kulshreshtha R  et al. A microRNA signature of hypoxia. Mol Cell Biol 27:1859-67 (2007). ChIP ; Human . PubMed: 17194750
  • Anderson CJ  et al. Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms. Oncogene 25:61-9 (2006). ChIP ; Human . PubMed: 16170363
  • Pescador N  et al. Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene. Biochem J 390:189-97 (2005). ChIP ; Human . PubMed: 15823097

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