Overview

  • Product nameAnti-HIP1R antibody
    See all HIP1R primary antibodies
  • Description
    Rabbit polyclonal to HIP1R
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide:

    QDHQLDKKDGIYPAQLVNY

    , corresponding to N terminal amino acids 264-282 of Human HIP1R

  • Positive control
    • P2 microsomal fraction from embryonic rat brain. Rat brain extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab79162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 116 kDa (predicted molecular weight: 119 kDa).

Target

  • FunctionComponent of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
  • Tissue specificityBrain, heart, kidney, pancreas, and liver, but not in lung or placenta.
  • Sequence similaritiesBelongs to the SLA2 family.
    Contains 1 ENTH (epsin N-terminal homology) domain.
    Contains 1 I/LWEQ domain.
  • DomainBinds F-actin via the talin-like I/LWEQ domain.
  • Cellular localizationCytoplasm > perinuclear region. Endomembrane system. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ14000 antibody
    • FLJ27022 antibody
    • HIP-12 antibody
    • Hip1 related antibody
    • HIP1-related protein antibody
    • HIP12 antibody
    • HIP1R antibody
    • HIP1R_HUMAN antibody
    • HIP3 antibody
    • Huntingtin Interacting Protein 1 Related antibody
    • Huntingtin interacting protein 12 antibody
    • Huntingtin-interacting protein 1-related protein antibody
    • Huntingtin-interacting protein 12 antibody
    • ILWEQ antibody
    • KIAA0655 antibody
    • MGC47513 antibody
    see all

Anti-HIP1R antibody images

References for Anti-HIP1R antibody (ab79162)

ab79162 has not yet been referenced specifically in any publications.

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