Overview

  • Product nameAnti-HIPK1 antibody
    See all HIPK1 primary antibodies
  • Description
    Rabbit polyclonal to HIPK1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 892-922 of Human HIPK1 (NP_689909.2, NP_852003.1, NP_938009.1, NP_938010.1).

  • Positive control
    • MCF7 cell line lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab113028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 131 kDa.

Target

  • FunctionMay play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.
  • Tissue specificityUbiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated. Phosphorylated and activated by JNK1.
  • Cellular localizationNucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • Database links
  • Alternative names
    • Hipk 1 antibody
    • Hipk1 antibody
    • HIPK1_HUMAN antibody
    • Homeodomain interacting protein kinase 1 antibody
    • Homeodomain interacting protein kinase 1 like protein antibody
    • Homeodomain-interacting protein kinase 1 antibody
    • Myak antibody
    • Nbak 2 antibody
    • Nbak2 antibody
    • Nuclear body associated kinase 2 antibody
    • Nuclear body associated kinase 2b antibody
    see all

Anti-HIPK1 antibody images

  • Lane 1 : Anti-HIPK1 antibody (ab113028) at 1/60 dilution
    Lane 2 : Anti-HIPK1 antibody (ab113028) at 1/250 dilution

    Lane 1 : MCF7 cell line lysate
    Lane 2 : MCF7 cell line lysate with blocking peptide

    Lysates/proteins at 12.5 µg per lane.


    Predicted band size : 131 kDa

References for Anti-HIPK1 antibody (ab113028)

ab113028 has not yet been referenced specifically in any publications.

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