Overview

  • Product nameAnti-HIPK1 antibody
    See all HIPK1 primary antibodies
  • Description
    Mouse monoclonal to HIPK1
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 330-430 of Human HIPK1

Properties

Applications

Our Abpromise guarantee covers the use of ab58136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.
    • Tissue specificityUbiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Autophosphorylated. Phosphorylated and activated by JNK1.
    • Cellular localizationNucleus. Cytoplasm. Predominantly nuclear.
    • Information by UniProt
    • Database links
    • Alternative names
      • Hipk 1 antibody
      • Hipk1 antibody
      • HIPK1_HUMAN antibody
      • Homeodomain interacting protein kinase 1 antibody
      • Homeodomain interacting protein kinase 1 like protein antibody
      • Homeodomain-interacting protein kinase 1 antibody
      • Myak antibody
      • Nbak 2 antibody
      • Nbak2 antibody
      • Nuclear body associated kinase 2 antibody
      • Nuclear body associated kinase 2b antibody
      see all

    Anti-HIPK1 antibody images

    • HIPK1 antibody (ab58136) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human salivary gland.
    • Western blot against tagged recombinant protein immunogen using ab58136 HIPK1 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    References for Anti-HIPK1 antibody (ab58136)

    This product has been referenced in:
    • Park BW  et al. Homeodomain-interacting Protein Kinase 1 (HIPK1) Expression in Breast Cancer Tissues. Jpn J Clin Oncol 42:1138-45 (2012). IHC-P . Read more (PubMed: 23071292) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab58136.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"