Anti-Histidase antibody (ab154063)
Key features and details
- Rabbit polyclonal to Histidase
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Histidase antibody -
Description
Rabbit polyclonal to Histidase -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rat, Chicken, Cow, Human -
Immunogen
Recombinant fragment corresponding to a region within internal sequence amino acids 209-489 of Human Histidase (UniProt ID: P42357).
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Positive control
- Mouse liver whole cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154063 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 73 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 73 kDa. |
Target
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Pathway
Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3. -
Involvement in disease
Histidinemia (HISTID) [MIM:235800]: Autosomal recessive disease characterized by increased histidine and histamine as well as decreased urocanic acid in body fluids. Note=The disease is caused by mutations affecting the gene represented in this entry. -
Sequence similarities
Belongs to the PAL/histidase family. -
Post-translational
modificationsContains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly. - Information by UniProt
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Database links
- Entrez Gene: 378924 Chicken
- Entrez Gene: 615205 Cow
- Entrez Gene: 3034 Human
- Entrez Gene: 15109 Mouse
- Entrez Gene: 29301 Rat
- Omim: 609457 Human
- SwissProt: A7YWP4 Cow
- SwissProt: P42357 Human
see all -
Alternative names
- HIS antibody
- hutH 1 antibody
- Hal antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab154063 has been referenced in 2 publications.
- Zhu H et al. Moderate UV Exposure Enhances Learning and Memory by Promoting a Novel Glutamate Biosynthetic Pathway in the Brain. Cell 173:1716-1727.e17 (2018). PubMed: 29779945
- Qian K et al. Expression of a glucagon-like peptide-1 analogue, as a therapeutic agent for type II diabetes, with enhanced bioactivity and increased N-terminal homogeneity in Pichia pastoris. Biotechnol Lett 37:2229-35 (2015). PubMed: 26160109