Anti-Histone H1oo (phospho S20 + S20) antibody (ab75319)

Overview

  • Product nameAnti-Histone H1oo (phospho S20 + S20) antibody
  • Description
    Rabbit polyclonal to Histone H1oo (phospho S20 + S20)
  • SpecificityReacts with mouse 32 kDa Histone H1oo phophorylated at serine 20
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Mouse Histone H1oo (N terminal) (phospho S20).
    Database link: Q8VIK3

Properties

Applications

Our Abpromise guarantee covers the use of ab75319 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/2000. Predicted molecular weight: 32 kDa.

Target

  • FunctionMay play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
  • Tissue specificityOocyte-specific.
  • Sequence similaritiesBelongs to the histone H1/H5 family.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
  • Cellular localizationCytoplasm. Nucleus. Chromosome.
  • Information by UniProt
  • Alternative names
    • H1FOO antibody
    • H1FOO_HUMAN antibody
    • Histone H1oo antibody
    • Oocyte-specific histone H1 antibody
    • Oocyte-specific linker histone H1 antibody
    • osH1 antibody
    see all

References for Anti-Histone H1oo (phospho S20 + S20) antibody (ab75319)

ab75319 has not yet been referenced specifically in any publications.

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