Anti-Histone H3 (acetyl K56) antibody [EPR996Y] (ab76307)

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ab76307 has been referenced in 34 publications.

  • Hawkins KE  et al. Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency. Mol Ther 25:427-442 (2017). PubMed: 28153093
  • Ioris RM  et al. SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity. Cell Rep 18:1858-1868 (2017). ChIP . PubMed: 28228253
  • Col E  et al. Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock. Sci Rep 7:5418 (2017). PubMed: 28710461
  • Ziegler-Birling C  et al. Dynamics of histone H3 acetylation in the nucleosome core during mouse pre-implantation development. Epigenetics 11:553-62 (2016). Mouse . PubMed: 26479850
  • Anderson MZ  et al. A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues. PLoS Genet 12:e1006353 (2016). PubMed: 27711197
  • Zhang X  et al. Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes. PLoS One 11:e0150175 (2016). WB . PubMed: 26918332
  • Gao X  et al. Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun 7:11960 (2016). IHC . PubMed: 27357947
  • Onyango DO  et al. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res 44:5702-16 (2016). WB . PubMed: 27084940
  • Pan H  et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res 26:190-205 (2016). WB, ChIP ; Human . PubMed: 26768768
  • Li G  et al. TLR4-mediated NF-?B signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis. Int J Mol Med 37:99-107 (2016). WB ; Mouse . PubMed: 26719855
  • Kugel S  et al. Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer. Cell Rep 13:479-88 (2015). WB, ChIP ; Mouse . PubMed: 26456828
  • Benard A  et al. Nuclear expression of histone deacetylases and their histone modifications predicts clinical outcome in colorectal cancer. Histopathology 66:270-82 (2015). PubMed: 25307864
  • Han L  et al. Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte. Sci Rep 5:15366 (2015). ICC/IF ; Mouse . PubMed: 26481302
  • Rothbart SB  et al. An Interactive Database for the Assessment of Histone Antibody Specificity. Mol Cell 59:502-11 (2015). PubMed: 26212453
  • Hagelkruys A  et al. Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development. Mol Cell Biol 36:462-74 (2015). WB . PubMed: 26598605
  • Zhang J  et al. SOX4 inhibits GBM cell growth and induces G0/G1 cell cycle arrest through Akt-p53 axis. BMC Neurol 14:207 (2014). WB ; Human . PubMed: 25366337
  • Hagelkruys A  et al. A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development 141:604-16 (2014). WB, IHC-P ; Mouse . PubMed: 24449838
  • Sakakibara N  et al. Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA. PLoS Pathog 9:e1003777 (2013). ICC/IF ; Human . PubMed: 24278023
  • Tropberger P  et al. Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer. Cell 152:859-72 (2013). WB ; Human . PubMed: 23415232
  • Kato H  et al. Spt6 prevents transcription-coupled loss of posttranslationally modified histone H3. Sci Rep 3:2186 (2013). PubMed: 23851719
  • Gräff J  et al. A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration. J Neurosci 33:8951-60 (2013). ICC/IF . PubMed: 23699506
  • Cantù C  et al. The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development 140:2377-86 (2013). PubMed: 23637336
  • Wells CE  et al. Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. PLoS One 8:e68915 (2013). WB ; Human . PubMed: 23894374
  • Gil R  et al. SIRT6 exhibits nucleosome-dependent deacetylase activity. Nucleic Acids Res 41:8537-8545 (2013). WB ; Human . PubMed: 23892288
  • Liu Y  et al. Oncogene Ras/phosphatidylinositol 3-kinase signaling targets histone H3 acetylation at lysine 56. J Biol Chem 287:41469-80 (2012). PubMed: 22982396
  • Drogaris P  et al. Histone deacetylase inhibitors globally enhance h3/h4 tail acetylation without affecting h3 lysine 56 acetylation. Sci Rep 2:220 (2012). WB ; Human . PubMed: 22355734
  • Gu B  et al. Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells. Cell Cycle 11:79-87 (2012). WB ; Human . PubMed: 22186018
  • Prieur A  et al. p53 and p16(INK4A) independent induction of senescence by chromatin-dependent alteration of S-phase progression. Nat Commun 2:473 (2011). PubMed: 21915115
  • Ogiwara H  et al. Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene 30:2135-46 (2011). PubMed: 21217779
  • Battu A  et al. ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation. Nucleic Acids Res 39:7931-45 (2011). PubMed: 21727091
  • Schwer B  et al. Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc Natl Acad Sci U S A 107:21790-4 (2010). WB ; Mouse . PubMed: 21098266
  • Turner EL  et al. The Saccharomyces cerevisiae anaphase-promoting complex interacts with multiple histone-modifying enzymes to regulate cell cycle progression. Eukaryot Cell 9:1418-31 (2010). WB ; Saccharomyces cerevisiae . PubMed: 20709786
  • Miller KM  et al. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nat Struct Mol Biol 17:1144-51 (2010). ICC/IF ; Human . PubMed: 20802485
  • Reynoird N  et al. Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J 29:2943-52 (2010). WB, ICC/IF ; Human . PubMed: 20676058


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