Histone H3 (acetyl K56) Quantification Kit (Fluorometric) (ab115115)

Overview

  • Product nameHistone H3 (acetyl K56) Quantification Kit (Fluorometric)
    See all Histone H3 (K56 acetylation) kits
  • Sample type
    Adherent cells, Suspension cells
  • Sensitivity
    0.4 ng/well
  • Range
    5 ng/well - 2000 ng/well
  • Assay time
    2h 30m
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: all Mammals
  • Product overview

    Acetylation of histones such histone H3 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H3 actylation. Histone H3 (acetyl K56) is cell cycle regulated, maintained upon replicative damage in a check-point manner and is essential for surviving DNA damage. H3 (acetyl K56) occurs normally during S-phase, and in absence of this modification, cellular survival following DNA damage is impaired.

    Abcam's Histone H3 (acetyl K56) Quantification Kit (Fluorometric) (ab115115) allows the experimenter to measure global acetylation of histone H3K56 quickly and consistently. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment and it is suitable for specifically measuring global histone H3K56 acetylation using a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.

  • Tested applicationsSuitable for: Functional Studiesmore details

Properties

    Applications

    Our Abpromise guarantee covers the use of ab115115 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Functional Studies Use at an assay dependent concentration.

    Protocols

    References for Histone H3 (acetyl K56) Quantification Kit (Fluorometric) (ab115115)

    ab115115 has not yet been referenced specifically in any publications.

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