Anti-Histone H3 (acetyl K9) antibody - ChIP Grade (ab4441)

Publishing research using ab4441? Please let us know so that we can cite the reference in this datasheet.

ab4441 has been referenced in 98 publications.

  • Shao Z  et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun 7:10869 (2016). PubMed: 26947130
  • Weyemi U  et al. The histone variant H2A.X is a regulator of the epithelial-mesenchymal transition. Nat Commun 7:10711 (2016). ChIP ; Human . PubMed: 26876487
  • Rao VK  et al. G9a promotes proliferation and inhibits cell cycle exit during myogenic differentiation. Nucleic Acids Res 44:8129-43 (2016). ChIP ; Mouse . PubMed: 27229136
  • Zhang ZQ  et al. Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice. Sci Rep 6:23912 (2016). ChIP, IHC-P, WB ; Mouse . PubMed: 27045575
  • Cuella-Martin R  et al. 53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms. Mol Cell 64:51-64 (2016). ChIP ; Human . PubMed: 27546791
  • Wang Y  et al. Repression of MYBL2 by Both microRNA858a and HY5 Leads to the Activation of Anthocyanin Biosynthetic Pathway in Arabidopsis. Mol Plant 9:1395-1405 (2016). PubMed: 27450422
  • Xiao X  et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun 6:8266 (2015). ChIP ; Mouse . PubMed: 26365427
  • Huang YH  et al. Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4. PLoS One 10:e0136453 (2015). WB ; Mouse . PubMed: 26305546
  • Riffo-Campos ÁL  et al. Nucleosome-specific, time-dependent changes in histone modifications during activation of the early growth response 1 (Egr1) gene. J Biol Chem 290:197-208 (2015). ChIP ; Mouse . PubMed: 25378406
  • Magri L  et al. c-Myc-dependent transcriptional regulation of cell cycle and nucleosomal histones during oligodendrocyte differentiation. Neuroscience 276:72-86 (2014). ChIP, ICC/IF ; Mouse . PubMed: 24502923
  • Chauvigné F  et al. Germ-line activation of the luteinizing hormone receptor directly drives spermiogenesis in a nonmammalian vertebrate. Proc Natl Acad Sci U S A 111:1427-32 (2014). PubMed: 24474769
  • Kisseljova NP  et al. DNA polymorphism and epigenetic marks modulate the affinity of a scaffold/matrix attachment region to the nuclear matrix. Eur J Hum Genet N/A:N/A (2014). ChIP ; Human . PubMed: 24448543
  • Sike A  et al. mRNA levels of related Abcb genes change opposite to each other upon histone deacetylase inhibition in drug-resistant rat hepatoma cells. PLoS One 9:e84915 (2014). ChIP ; Rat . PubMed: 24409311
  • Mohan RD  et al. Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration. Genes Dev 28:259-72 (2014). Drosophila melanogaster . PubMed: 24493646
  • McLaughlin N  et al. In situ histone landscape of nephrogenesis. Epigenetics 9:222-35 (2014). WB ; Mouse . PubMed: 24169366
  • Armelin-Correa LM  et al. Nuclear compartmentalization of odorant receptor genes. Proc Natl Acad Sci U S A 111:2782-7 (2014). PubMed: 24550308
  • Di Cerbo V  et al. Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription. Elife 3:e01632 (2014). IP ; Human . PubMed: 24668167
  • Fujiwara T  et al. 3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation. J Biol Chem 289:8121-34 (2014). PubMed: 24492606
  • Jiang L  et al. ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells. PLoS One 9:e94187 (2014). CHIPseq ; Mouse . PubMed: 24714595
  • Mosesson Y  et al. Divergence and selectivity of expression-coupled histone modifications in budding yeasts. PLoS One 9:e101538 (2014). CHIPseq ; Saccharomyces cerevisiae . PubMed: 25007273
  • Peng X  et al. TELP, a sensitive and versatile library construction method for next-generation sequencing. Nucleic Acids Res N/A:N/A (2014). ChIP ; Mouse . PubMed: 25223787
  • Bonnet J  et al. The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription. Genes Dev 28:1999-2012 (2014). PubMed: 25228644
  • Jose CC  et al. Epigenetic dysregulation by nickel through repressive chromatin domain disruption. Proc Natl Acad Sci U S A 111:14631-6 (2014). PubMed: 25246589
  • Oestreich KJ  et al. Bcl-6 directly represses the gene program of the glycolysis pathway. Nat Immunol 15:957-64 (2014). PubMed: 25194422
  • Sharma A  et al. Calcium-mediated histone modifications regulate alternative splicing in cardiomyocytes. Proc Natl Acad Sci U S A 111:E4920-8 (2014). PubMed: 25368158
  • Tropberger P  et al. Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer. Cell 152:859-72 (2013). ChIP ; Human . PubMed: 23415232
  • Wolf G  et al. Epigenetic marking and repression of porcine endogenous retroviruses. J Gen Virol 94:960-70 (2013). ChIP . PubMed: 23324470
  • Bertucci PY  et al. Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation. Nucleic Acids Res 41:6072-86 (2013). ChIP . PubMed: 23640331
  • Hamed M  et al. Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation. Sci Rep 3:2390 (2013). ChIP . PubMed: 23928680
  • Wolf L  et al. Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Nucleic Acids Res N/A:N/A (2013). ICC/IF ; Mouse . PubMed: 24038357
  • Ravnskjaer K  et al. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest 123:4318-28 (2013). WB, IP . PubMed: 24051374
  • Pankotai T  et al. Functional characterization and gene expression profiling of Drosophila melanogaster short dADA2b isoform-containing dSAGA complexes. BMC Genomics 14:44 (2013). WB, IHC (PFA fixed) ; Drosophila melanogaster . PubMed: 23336284
  • Suzuki M  et al. Differential type I interferon-dependent transgene silencing of helper-dependent adenoviral vs. adeno-associated viral vectors in vivo. Mol Ther 21:796-805 (2013). PubMed: 23319058
  • Ladopoulos V  et al. The Histone Methyltransferase KMT2B Is Required for RNA Polymerase II Association and Protection from DNA Methylation at the MagohB CpG Island Promoter. Mol Cell Biol 33:1383-93 (2013). ChIP . PubMed: 23358417
  • Dreveny I  et al. The double PHD finger domain of MOZ/MYST3 induces a-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res N/A:N/A (2013). WB ; Human . PubMed: 24150941
  • Wang T  et al. The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation. Blood 122:2812-22 (2013). ChIP ; Mouse . PubMed: 24014243
  • Burke SJ  et al. Regulation of iNOS gene transcription by IL-1ß and IFN-? requires a coactivator exchange mechanism. Mol Endocrinol 27:1724-42 (2013). IP . PubMed: 24014650
  • Lan L  et al. Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin. Nucleic Acids Res N/A:N/A (2013). ICC/IF ; Human . PubMed: 24293652
  • Rajabi H  et al. MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells. J Biol Chem 287:10703-13 (2012). ChIP ; Human . PubMed: 22318732
  • Demmerle J  et al. The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity. J Biol Chem 287:22080-8 (2012). PubMed: 22570481
  • Kloth M  et al. The SNP rs6441224 influences transcriptional activity and prognostically relevant hypermethylation of RARRES1 in prostate cancer. Int J Cancer 131:E897-904 (2012). PubMed: 22573467
  • Wu M  et al. Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation. J Neurosci 32:6651-64 (2012). PubMed: 22573687
  • Fang TC  et al. Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response. J Exp Med 209:661-9 (2012). PubMed: 22412156
  • Kim JM  et al. Transition of chromatin status during the process of recovery from drought stress in Arabidopsis thaliana. Plant Cell Physiol 53:847-56 (2012). PubMed: 22505693
  • Wells MB  et al. Caenorhabditis elegans dosage compensation regulates histone H4 chromatin state on X chromosomes. Mol Cell Biol 32:1710-9 (2012). PubMed: 22393255
  • Parker JB  et al. A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function. Mol Cell Biol 32:1654-70 (2012). ChIP . PubMed: 22371484
  • Bodai L  et al. Ecdysone induced gene expression is associated with acetylation of histone H3 lysine 23 in Drosophila melanogaster. PLoS One 7:e40565 (2012). ChIP . PubMed: 22808194
  • Lichtinger M  et al. RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis. EMBO J 31:4318-33 (2012). ChIP . PubMed: 23064151
  • Teif VB  et al. Genome-wide nucleosome positioning during embryonic stem cell development. Nat Struct Mol Biol 19:1185-92 (2012). PubMed: 23085715
  • Krogan NT  et al. APETALA2 negatively regulates multiple floral organ identity genes in Arabidopsis by recruiting the co-repressor TOPLESS and the histone deacetylase HDA19. Development 139:4180-90 (2012). PubMed: 23034631
  • Cowper-Sal lari R  et al. Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nat Genet 44:1191-8 (2012). ChIP . PubMed: 23001124
  • Hong GM & Bain LJ Sodium arsenite represses the expression of myogenin in C2C12 mouse myoblast cells through histone modifications and altered expression of Ezh2, Glp, and Igf-1. Toxicol Appl Pharmacol 260:250-9 (2012). ChIP ; Mouse . PubMed: 22426358
  • Singh NP  et al. Epigenetic profile of the euchromatic region of human Y chromosome. Nucleic Acids Res 39:3594-606 (2011). ChIP ; Human . PubMed: 21252296
  • Takeda Y  et al. Retinoic acid-related orphan receptor ? directly regulates neuronal PAS domain protein 2 transcription in vivo. Nucleic Acids Res 39:4769-82 (2011). ChIP ; Mouse . PubMed: 21317191
  • Alhashem Y  et al. Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal {beta}-globin genes through direct promoter binding. J Biol Chem : (2011). ChIP ; Mouse . PubMed: 21610079
  • Trejbalová K  et al. Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin. Nucleic Acids Res 39:8728-39 (2011). ChIP . PubMed: 21771862
  • Chen S  et al. Histone Deacetylase (HDAC) Activity Is Critical for Embryonic Kidney Gene Expression, Growth, and Differentiation. J Biol Chem 286:32775-89 (2011). ChIP . PubMed: 21778236
  • Taraborrelli C  et al. TNFR1 is essential for CD40, but not for lipopolysaccharide-induced sickness behavior and clock gene dysregulation. Brain Behav Immun 25:434-42 (2011). ChIP ; Mouse . PubMed: 21074606
  • Lalmansingh AS  et al. TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo. J Biol Chem 286:10970-82 (2011). PubMed: 21252238
  • Zhang CC  et al. RPL1, a Gene Involved in Epigenetic Processes Regulates Phenotypic Plasticity in Rice. Mol Plant : (2011). PubMed: 22131052
  • Ram O  et al. Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell 147:1628-39 (2011). CHIPseq ; Human . PubMed: 22196736
  • Verdeguer F  et al. A mitotic transcriptional switch in polycystic kidney disease. Nat Med 16:106-10 (2010). ChIP ; Mouse . PubMed: 19966811
  • Sun J & Li R Human negative elongation factor activates transcription and regulates alternative transcription initiation. J Biol Chem 285:6443-52 (2010). ChIP ; Human . PubMed: 20028984
  • Suzuki M  et al. MyD88-dependent silencing of transgene expression during the innate and adaptive immune response to helper-dependent adenovirus. Hum Gene Ther 21:325-36 (2010). PubMed: 19824822
  • Ribarska T  et al. Epigenetic inactivation of the placentally imprinted tumor suppressor gene TFPI2 in prostate carcinoma. Cancer Genomics Proteomics 7:51-60 (2010). ChIP ; Human . PubMed: 20335518
  • Sandoval J  et al. Ordered transcriptional factor recruitment and epigenetic regulation of tnf-alpha in necrotizing acute pancreatitis. Cell Mol Life Sci 67:1687-97 (2010). ChIP ; Rat . PubMed: 20130956
  • Liefke R  et al. Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex. Genes Dev 24:590-601 (2010). ChIP ; Mouse . PubMed: 20231316
  • Lamprecht B  et al. Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma. Nat Med 16:571-9, 1p following 579 (2010). ChIP ; Human . PubMed: 20436485
  • Liu F  et al. Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate. Oncogene : (2010). ChIP ; Human . PubMed: 20440268
  • Earley KW  et al. Mechanisms of HDA6-mediated rRNA gene silencing: suppression of intergenic Pol II transcription and differential effects on maintenance versus siRNA-directed cytosine methylation. Genes Dev 24:1119-32 (2010). ChIP . PubMed: 20516197
  • Heintzman ND  et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459:108-12 (2009). ChIP/Chip ; Human . PubMed: 19295514
  • Gargiulo G  et al. NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation. Dev Cell 16:466-81 (2009). ChIP . PubMed: 19289091
  • Yu Z  et al. The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J 28:1890-903 (2009). ChIP ; Human . PubMed: 19494835
  • Bougdour A  et al. Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites. J Exp Med 206:953-66 (2009). WB ; Toxoplasma gondii . PubMed: 19349466
  • Zsindely N  et al. The loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes. Nucleic Acids Res 37:6665-80 (2009). WB, ICC/IF, ChIP ; Drosophila melanogaster . PubMed: 19740772
  • Menigatti M  et al. The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis. Mol Cancer 8:124 (2009). ChIP ; Human . PubMed: 20015382
  • Michishita E  et al. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature : (2008). WB, ChIP ; Human . PubMed: 18337721
  • Dunican DS  et al. xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function. Development 135:1295-302 (2008). WB . PubMed: 18305009
  • Gurtner A  et al. NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue. PLoS ONE 3:e2047 (2008). ICC/IF, ChIP ; Human, Mouse . PubMed: 18431504
  • Wang Z  et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 40:897-903 (2008). CHIPseq . PubMed: 18552846
  • Cebrat M  et al. Mechanism of lymphocyte-specific inactivation of RAG-2 intragenic promoter of NWC: implications for epigenetic control of RAG locus. Mol Immunol 45:2297-306 (2008). ChIP . PubMed: 18166226
  • Chou SD & Tomasi TB Spatial distribution of histone methylation during MHC class II expression. Mol Immunol 45:971-80 (2008). PubMed: 17850872
  • Taylor P & Hardin PE Rhythmic E-box binding by CLK-CYC controls daily cycles in per and tim transcription and chromatin modifications. Mol Cell Biol 28:4642-52 (2008). ChIP ; Drosophila melanogaster . PubMed: 18474612
  • Sadikovic B  et al. Genome-wide H3K9 Histone Acetylation Profiles Are Altered in Benzopyrene-treated MCF7 Breast Cancer Cells. J Biol Chem 283:4051-60 (2008). IP ; Human . PubMed: 18065415
  • Shimada M  et al. Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression. Cell 132:221-32 (2008). ChIP ; Mouse . PubMed: 18243098
  • Zhou Z  et al. Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases. J Virol 81:7749-58 (2007). ChIP ; Human . PubMed: 17507495
  • Hamon MA  et al. Histone modifications induced by a family of bacterial toxins. Proc Natl Acad Sci U S A 104:13467-72 (2007). PubMed: 17675409
  • Tavner F  et al. Targeting an E2F site in the mouse genome prevents promoter silencing in quiescent and post-mitotic cells. Oncogene 26:2727-35 (2007). PubMed: 17072340
  • Krysinska H  et al. A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. Mol Cell Biol 27:878-87 (2007). ChIP ; Mouse . PubMed: 17116688
  • Vaquero A  et al. SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature 450:440-4 (2007). ICC/IF ; Mouse . PubMed: 18004385
  • Caballero R  et al. Combinatorial effects of splice variants modulate function of Aiolos. J Cell Sci 120:2619-30 (2007). WB ; Human . PubMed: 17646674
  • Guccione E  et al. Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol 8:764-70 (2006). PubMed: 16767079
  • Sripathy SP  et al. The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression. Mol Cell Biol 26:8623-38 (2006). ChIP . PubMed: 16954381
  • Boix-Chornet M  et al. Release of hypoacetylated and trimethylated histone H4 is an epigenetic marker of early apoptosis. J Biol Chem 281:13540-7 (2006). PubMed: 16531610
  • Adhvaryu KK  et al. Methylation of histone H3 lysine 36 is required for normal development in Neurospora crassa. Eukaryot Cell 4:1455-64 (2005). WB ; Neurospora crassa . PubMed: 16087750
  • Minoda A  et al. BAF53/Arp4 homolog Alp5 in fission yeast is required for histone H4 acetylation, kinetochore-spindle attachment, and gene silencing at centromere. Mol Biol Cell 16:316-27 (2005). WB ; Schizosaccharomyces pombe . PubMed: 15483052
  • Seligson DB  et al. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435:1262-6 (2005). PubMed: 15988529
  • Liu CL  et al. Single-nucleosome mapping of histone modifications in S. cerevisiae. PLoS Biol 3:e328 (2005). PubMed: 16122352

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