Anti-Histone H3 (citrulline R2 + R8 + R17) antibody - ChIP Grade (ab5103)

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ab5103 has been referenced in 26 publications.

  • Zenaro E  et al. Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin. Nat Med N/A:N/A (2015). PubMed: 26214837
  • Gavillet M  et al. Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples. Am J Hematol 90:1155-8 (2015). Flow Cyt . PubMed: 26347989
  • Mizurini DM  et al. Salivary Thromboxane A2-Binding Proteins from Triatomine Vectors of Chagas Disease Inhibit Platelet-Mediated Neutrophil Extracellular Traps (NETs) Formation and Arterial Thrombosis. PLoS Negl Trop Dis 9:e0003869 (2015). Mouse . PubMed: 26110417
  • Waisberg M  et al. Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis. PLoS Pathog 10:e1004338 (2014). ICC/IF ; Human . PubMed: 25211214
  • Branzk N  et al. Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat Immunol 15:1017-25 (2014). PubMed: 25217981
  • Hirose T  et al. Presence of neutrophil extracellular traps and citrullinated histone H3 in the bloodstream of critically ill patients. PLoS One 9:e111755 (2014). ICC/IF ; Human . PubMed: 25392950
  • Dwivedi N  et al. Deimination of linker histones links neutrophil extracellular trap release with autoantibodies in systemic autoimmunity. FASEB J 28:2840-51 (2014). WB ; Human . PubMed: 24671707
  • Chen G  et al. Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease. Blood 123:3818-27 (2014). PubMed: 24620350
  • Deplus R  et al. Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation. Nucleic Acids Res N/A:N/A (2014). WB . PubMed: 24957603
  • Savchenko AS  et al. VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice. Blood 123:141-8 (2014). ICC/IF ; Mouse . PubMed: 24200682
  • Knight JS  et al. Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. J Clin Invest 123:2981-93 (2013). PubMed: 23722903
  • Barrientos L  et al. An improved strategy to recover large fragments of functional human neutrophil extracellular traps. Front Immunol 4:166 (2013). PubMed: 23805143
  • Martinod K  et al. Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice. Proc Natl Acad Sci U S A 110:8674-9 (2013). IHC, ICC/IF ; Mouse . PubMed: 23650392
  • Darrah E  et al. Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity. Sci Transl Med 5:186ra65 (2013). WB ; Human . PubMed: 23698378
  • Neeli I & Radic M Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release. Front Immunol 4:38 (2013). Human . PubMed: 23430963
  • Thomas GM  et al. Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice. Blood 119:6335-43 (2012). IHC-Fr ; Mouse . PubMed: 22596262
  • Wang Y  et al. Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity. J Biol Chem 287:25941-53 (2012). WB, ChIP . PubMed: 22605338
  • Douda DN  et al. Innate immune collectin surfactant protein d simultaneously binds both neutrophil extracellular traps and carbohydrate ligands and promotes bacterial trapping. J Immunol 187:1856-65 (2011). WB ; Mouse . PubMed: 21724991
  • Li P  et al. PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. J Exp Med 207:1853-62 (2010). WB, ICC/IF ; Mouse . PubMed: 20733033
  • Wang Y  et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol 184:205-13 (2009). WB ; Human . PubMed: 19153223
  • Denis H  et al. Functional connection between deimination and deacetylation of histones. Mol Cell Biol 29:4982-93 (2009). WB, ChIP/Chip . PubMed: 19581286
  • Neeli I  et al. Histone deimination as a response to inflammatory stimuli in neutrophils. J Immunol 180:1895-902 (2008). WB, ICC/IF ; Human . PubMed: 18209087
  • Li P  et al. Regulation of p53 target gene expression by peptidylarginine deiminase 4. Mol Cell Biol 28:4745-58 (2008). ChIP ; Human . PubMed: 18505818
  • Miao F  et al. Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17. Mol Endocrinol 20:1562-73 (2006). PubMed: 16497732
  • Mastronardi FG  et al. Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci 26:11387-96 (2006). PubMed: 17079667
  • Cuthbert GL  et al. Histone deimination antagonizes arginine methylation. Cell 118:545-53 (2004). PubMed: 15339660