Anti-Histone H3 (di methyl K4) antibody - ChIP Grade (ab7766)

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ab7766 has been referenced in 98 publications.

  • Bledau AS  et al. The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation. Development 141:1022-35 (2014). PubMed: 24550110
  • Stimpson KM  et al. Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. PLoS One 9:e92432 (2014). ChIP ; Human . PubMed: 24662969
  • Henson DM  et al. A silencer-proximal intronic region is required for sustained CD4 expression in postselection thymocytes. J Immunol 192:4620-7 (2014). ChIP . PubMed: 24729613
  • Brahmachary M  et al. Digital genotyping of macrosatellites and multicopy genes reveals novel biological functions associated with copy number variation of large tandem repeats. PLoS Genet 10:e1004418 (2014). CHIPseq ; Human . PubMed: 24945355
  • Liu D & Zempleni J Transcriptional regulation of the albumin gene depends on the removal of histone methylation marks by the FAD-dependent monoamine oxidase lysine-specific demethylase 1 in HepG2 human hepatocarcinoma cells. J Nutr 144:997-1001 (2014). Human . PubMed: 24744315
  • Rafehi H  et al. Vascular histone deacetylation by pharmacological HDAC inhibition. Genome Res 24:1271-84 (2014). PubMed: 24732587
  • Liu D & Zempleni J Low activity of LSD1 elicits a pro-inflammatory gene expression profile in riboflavin-deficient human T Lymphoma Jurkat cells. Genes Nutr 9:422 (2014). WB, ChIP ; Human . PubMed: 25103574
  • Heidari N  et al. Genome-wide map of regulatory interactions in the human genome. Genome Res 24:1905-17 (2014). Human . PubMed: 25228660
  • Ginsburg DS  et al. NuA4 links methylation of histone H3 lysines 4 and 36 to acetylation of histones H4 and H3. J Biol Chem 289:32656-70 (2014). PubMed: 25301943
  • Zhang X  et al. The role of antisense long noncoding RNA in small RNA-triggered gene activation. RNA 20:1916-28 (2014). ChIP . PubMed: 25344398
  • Malik P  et al. NET23/STING promotes chromatin compaction from the nuclear envelope. PLoS One 9:e111851 (2014). PubMed: 25386906
  • Suzuki J  et al. A novel small compound SH-2251 suppresses Th2 cell-dependent airway inflammation through selective modulation of chromatin status at the Il5 gene locus. PLoS One 8:e61785 (2013). ChIP . PubMed: 23613936
  • Takizawa F  et al. Glucose-independent persistence of PAI-1 gene expression and H3K4 tri-methylation in type 1 diabetic mouse endothelium: implication in metabolic memory. Biochem Biophys Res Commun 433:66-72 (2013). PubMed: 23454124
  • Sayegh J  et al. Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J Biol Chem 288:9408-17 (2013). PubMed: 23408432
  • Sadhu MJ  et al. Nutritional control of epigenetic processes in yeast and human cells. Genetics 195:831-44 (2013). Human . PubMed: 23979574
  • Schwab KR  et al. Arrested spermatogenesis and evidence for DNA damage in PTIP mutant testes. Dev Biol 373:64-71 (2013). PubMed: 23063797
  • Vasanthi D  et al. A functionally conserved Polycomb response element from mouse HoxD complex responds to heterochromatin factors. Sci Rep 3:3011 (2013). ChIP . PubMed: 24145990
  • de Vries M  et al. Human male meiotic sex chromosome inactivation. PLoS One 7:e31485 (2012). ICC/IF ; Human . PubMed: 22355370
  • Wong PP  et al. Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A). Mol Cell Biol 32:1633-44 (2012). ChIP . PubMed: 22371483
  • Peterson KA  et al. Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev 26:2802-16 (2012). PubMed: 23249739
  • Wu SF  et al. Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm. Genome Res 21:578-89 (2011). WB . PubMed: 21383318
  • Xiao Y  et al. Caenorhabditis elegans chromatin-associated proteins SET-2 and ASH-2 are differentially required for histone H3 Lys 4 methylation in embryos and adult germ cells. Proc Natl Acad Sci U S A 108:8305-10 (2011). PubMed: 21527717
  • Ovesen JL  et al. Aryl hydrocarbon receptor ligands of widely different toxic equivalency factors induce similar histone marks in target gene chromatin. Toxicol Sci 121:123-31 (2011). ChIP ; Mouse . PubMed: 21292640
  • Kwon DW & Ahn SH Role of yeast JmjC-domain containing histone demethylases in actively transcribed regions. Biochem Biophys Res Commun 410:614-9 (2011). PubMed: 21684259
  • Lin C  et al. AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Mol Cell 37:429-37 (2010). WB . PubMed: 20159561
  • Steger DJ  et al. Propagation of adipogenic signals through an epigenomic transition state. Genes Dev 24:1035-44 (2010). ChIP/Chip . PubMed: 20478996
  • Punga T & Bühler M Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation. EMBO Mol Med 2:120-9 (2010). ChIP ; Human . PubMed: 20373285
  • Kim JH  et al. Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. Genome Res 19:533-44 (2009). PubMed: 19141594
  • Caslini C  et al. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol 29:4519-26 (2009). PubMed: 19528237
  • Yeap LS  et al. ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage. Epigenetics Chromatin 2:12 (2009). WB . PubMed: 19811652
  • Nuytten M  et al. The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing. Oncogene 27:1449-60 (2008). PubMed: 17724462
  • Wang LH  et al. Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma 117:123-35 (2008). PubMed: 17989990
  • Vitaliano-Prunier A  et al. Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation. Nat Cell Biol 10:1365-71 (2008). WB, ChIP ; Saccharomyces cerevisiae . PubMed: 18849979
  • Mancio-Silva L  et al. Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum. J Cell Sci 121:2046-53 (2008). ICC/IF ; Plasmodium falciparum . PubMed: 18525026
  • Seneda MM  et al. Developmental regulation of histone H3 methylation at lysine 4 in the porcine ovary. Reproduction 135:829-38 (2008). PubMed: 18502896
  • Cebrat M  et al. Mechanism of lymphocyte-specific inactivation of RAG-2 intragenic promoter of NWC: implications for epigenetic control of RAG locus. Mol Immunol 45:2297-306 (2008). ChIP . PubMed: 18166226
  • Haussecker D  et al. Capped small RNAs and MOV10 in human hepatitis delta virus replication. Nat Struct Mol Biol 15:714-21 (2008). WB ; Human . PubMed: 18552826
  • Meissner A  et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature : (2008). ChIP ; Mouse . PubMed: 18600261
  • Yu W  et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 451:202-6 (2008). ChIP ; Human . PubMed: 18185590
  • Lupien M  et al. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 132:958-70 (2008). ChIP, ChIP/Chip ; Human . PubMed: 18358809
  • Dahl JA & Collas P MicroChIP--a rapid micro chromatin immunoprecipitation assay for small cell samples and biopsies. Nucleic Acids Res 36:e15 (2008). ChIP ; Human . PubMed: 18202078
  • Larschan E  et al. MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Mol Cell 28:121-33 (2007). ChIP/Chip ; Drosophila melanogaster . PubMed: 17936709
  • Xiang Y  et al. JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc Natl Acad Sci U S A 104:19226-31 (2007). Zebrafish . PubMed: 18048344
  • Rincón-Arano H  et al. Protection against telomeric position effects by the chicken cHS4 beta-globin insulator. Proc Natl Acad Sci U S A 104:14044-9 (2007). PubMed: 17715059
  • De Santa F  et al. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 130:1083-94 (2007). WB, ICC/IF ; Human . PubMed: 17825402
  • Ingvarsdottir K  et al. Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Mol Cell Biol 27:7856-64 (2007). PubMed: 17875926
  • Scibetta AG  et al. Functional analysis of the transcription repressor PLU-1/JARID1B. Mol Cell Biol 27:7220-35 (2007). PubMed: 17709396
  • Schnekenburger M  et al. Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. Mol Cell Biol 27:7089-101 (2007). ChIP ; Mouse . PubMed: 17682057
  • Sarcinella E  et al. Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. Mol Cell Biol 27:6457-68 (2007). WB ; Human . PubMed: 17636032
  • Sullivan KE  et al. Epigenetic regulation of tumor necrosis factor alpha. Mol Cell Biol 27:5147-60 (2007). ChIP ; Human . PubMed: 17515611
  • Rinn JL  et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129:1311-23 (2007). ChIP . PubMed: 17604720
  • Vermeulen M  et al. Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell 131:58-69 (2007). WB ; Human . PubMed: 17884155
  • Liu Y  et al. RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev 21:1530-45 (2007). IP ; Tetrahymena . PubMed: 17575054
  • Koch CM  et al. The landscape of histone modifications across 1% of the human genome in five human cell lines. Genome Res 17:691-707 (2007). ChIP/Chip ; Human . PubMed: 17567990
  • Taverna SD  et al. Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A 104:2086-91 (2007). WB ; Tetrahymena . PubMed: 17284592
  • Kiskinis E  et al. RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes. EMBO J 26:4831-40 (2007). ChIP ; Mouse . PubMed: 17972916
  • Agger K  et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449:731-4 (2007). WB, ICC/IF ; Human . PubMed: 17713478
  • Godmann M  et al. Dynamic regulation of histone H3 methylation at lysine 4 in mammalian spermatogenesis. Biol Reprod 77:754-64 (2007). IHC-P ; Mouse, Marmoset (common) . PubMed: 17634443
  • Roh TY  et al. Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns. Genome Res 17:74-81 (2007). PubMed: 17135569
  • Barski A  et al. High-resolution profiling of histone methylations in the human genome. Cell 129:823-37 (2007). PubMed: 17512414
  • Brinkman AB  et al. DNA methylation immediately adjacent to active histone marking does not silence transcription. Nucleic Acids Res 35:801-11 (2007). PubMed: 17202157
  • Freberg CT  et al. Epigenetic Reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract. Mol Biol Cell 18:1543-53 (2007). PubMed: 17314394
  • Dahl JA & Collas P Q2ChIP, a quick and quantitative chromatin immunoprecipitation assay, unravels epigenetic dynamics of developmentally regulated genes in human carcinoma cells. Stem Cells 25:1037-46 (2007). PubMed: 17272500
  • Rybtsova N  et al. Transcription-coupled deposition of histone modifications during MHC class II gene activation. Nucleic Acids Res 35:3431-41 (2007). PubMed: 17478518
  • Rathke C  et al. Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila. J Cell Sci 120:1689-700 (2007). PubMed: 17452629
  • Dul BE & Walworth NC The plant homeodomain fingers of fission yeast Msc1 exhibit E3 ubiquitin ligase activity. J Biol Chem 282:18397-406 (2007). WB ; Saccharomyces cerevisiae . PubMed: 17456468
  • Maruyama T  et al. Histone H2B mutations in inner region affect ubiquitination, centromere function, silencing and chromosome segregation. EMBO J 25:2420-31 (2006). PubMed: 16688222
  • Torres-Padilla ME  et al. Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos. Int J Dev Biol 50:455-61 (2006). PubMed: 16586346
  • Nishijima H  et al. Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and Clr4 histone methyltransferase in Schizosaccharomyces pombe. Mol Biol Cell 17:2524-36 (2006). PubMed: 16540522
  • Guccione E  et al. Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol 8:764-70 (2006). PubMed: 16767079
  • Tripic T  et al. The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation. Biochem Biophys Res Commun 339:905-14 (2006). PubMed: 16329992
  • Dou Y  et al. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol 13:713-9 (2006). PubMed: 16878130
  • Dreijerink KM  et al. Menin links estrogen receptor activation to histone H3K4 trimethylation. Cancer Res 66:4929-35 (2006). PubMed: 16651450
  • Yan C & Boyd DD Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression. Mol Cell Biol 26:6357-71 (2006). ChIP . PubMed: 16914722
  • Loppin B  et al. The histone H3.3 chaperone HIRA is essential for chromatin assembly in the male pronucleus. Nature 437:1386-90 (2005). ICC/IF ; Drosophila melanogaster . PubMed: 16251970
  • Pokholok DK  et al. Genome-wide map of nucleosome acetylation and methylation in yeast. Cell 122:517-27 (2005). PubMed: 16122420
  • Ozdemir A  et al. Characterization of lysine 56 of histone H3 as an acetylation site in Saccharomyces cerevisiae. J Biol Chem 280:25949-52 (2005). PubMed: 15888442
  • Lefevre P  et al. Differentiation-dependent alterations in histone methylation and chromatin architecture at the inducible chicken lysozyme gene. J Biol Chem 280:27552-60 (2005). PubMed: 15923188
  • Wysocka J  et al. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121:859-72 (2005). PubMed: 15960974
  • Liu CL  et al. Single-nucleosome mapping of histone modifications in S. cerevisiae. PLoS Biol 3:e328 (2005). PubMed: 16122352
  • Morillon A  et al. Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription. Mol Cell 18:723-34 (2005). PubMed: 15949446
  • Farris SD  et al. Transcription-induced chromatin remodeling at the c-myc gene involves the local exchange of histone H2A.Z. J Biol Chem 280:25298-303 (2005). PubMed: 15878876
  • Seligson DB  et al. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435:1262-6 (2005). PubMed: 15988529
  • He J  et al. Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells. J Virol 79:13497-508 (2005). ChIP . PubMed: 16227270
  • Rodriguez-Jato S  et al. Characterization of cis- and trans-acting elements in the imprinted human SNURF-SNRPN locus. Nucleic Acids Res 33:4740-53 (2005). ChIP ; Human . PubMed: 16116039
  • Schlichter A & Cairns BR Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains. EMBO J 24:1222-31 (2005). PubMed: 15775977
  • Alsford S & Horn D Trypanosomatid histones. Mol Microbiol 53:365-72 (2004). PubMed: 15228519
  • Daniel JA  et al. Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription. J Biol Chem 279:1867-71 (2004). PubMed: 14660634
  • Schneider R  et al. Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nat Cell Biol 6:73-7 (2004). PubMed: 14661024
  • Li T  et al. Activating and silencing histone modifications form independent allelic switch regions in the imprinted Gnas gene. Hum Mol Genet 13:741-50 (2004). PubMed: 14962976
  • Dichtl B  et al. Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation. RNA 10:965-77 (2004). PubMed: 15146080
  • Yamashita M  et al. Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells. J Biol Chem 279:39454-64 (2004). PubMed: 15258154
  • Sullivan BA & Karpen GH Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin. Nat Struct Mol Biol 11:1076-83 (2004). PubMed: 15475964
  • Roguev A  et al. High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. J Biol Chem 278:8487-93 (2003). PubMed: 12488447
  • Reinke H & Hörz W Histones are first hyperacetylated and then lose contact with the activated PHO5 promoter. Mol Cell 11:1599-607 (2003). PubMed: 12820972
  • Morillon A  et al. Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115:425-35 (2003). PubMed: 14622597
  • Santos-Rosa H  et al. Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin. Mol Cell 12:1325-32 (2003). PubMed: 14636589
  • Dover J  et al. Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277:28368-71 (2002). PubMed: 12070136

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