Anti-Histone H3 (tri methyl K27) antibody [mAbcam 6002] - ChIP Grade (ab6002)

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ab6002 has been referenced in 380 publications.

  • Oittinen M  et al. Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia. Stem Cells 35:445-457 (2017). WB, ChIP . PubMed: 27570105
  • Ye Y  et al. Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos. Cell Death Differ 24:409-420 (2017). ChIP ; Drosophila melanogaster . PubMed: 27858939
  • Anderson L  et al. Histone deacetylase inhibition modulates histone acetylation at gene promoter regions and affects genome-wide gene transcription in Schistosoma mansoni. PLoS Negl Trop Dis 11:e0005539 (2017). WB, ChIP ; Schistosoma mansoni . PubMed: 28406899
  • Di Giorgio E  et al. The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness. PLoS Genet 13:e1006752 (2017). ChIP ; Human . PubMed: 28419090
  • Xun J  et al. JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity. Oncotarget 8:21918-21929 (2017). WB ; Human . PubMed: 28423536
  • Ali T  et al. Chromatin binding of Gcn5 in Drosophila is largely mediated by CP190. Nucleic Acids Res 45:2384-2395 (2017). IP ; Drosophila melanogaster . PubMed: 27903907
  • Pan G  et al. PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c. Nucleic Acids Res 45:2408-2422 (2017). ChIP ; Human . PubMed: 27932482
  • Kim DH & Sung S The Binding Specificity of the PHD-Finger Domain of VIN3 Moderates Vernalization Response. Plant Physiol 173:1258-1268 (2017). ChIP ; Arabidopsis thaliana . PubMed: 27999085
  • Ohshima K  et al. Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer. Sci Rep 7:45504 (2017). ChIP ; Human . PubMed: 28358054
  • Zhu XX  et al. Jarid2 is essential for the maintenance of tumor initiating cells in bladder cancer. Oncotarget 8:24483-24490 (2017). ChIP ; Human . PubMed: 28445934
  • Jiao S  et al. VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer. Nat Commun 8:14058 (2017). WB ; Human . PubMed: 28051067
  • Kim JJ  et al. Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells. Sci Rep 7:39406 (2017). WB, Immunomicroscopy, IHC (PFA fixed) ; Human . PubMed: 28051095
  • Seo W  et al. Distinct requirement of Runx complexes for TCRß enhancer activation at distinct developmental stages. Sci Rep 7:41351 (2017). ChIP ; Mouse . PubMed: 28150718
  • Lo YH  et al. Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine. Cell Mol Gastroenterol Hepatol 3:51-71 (2017). ChIP ; Human . PubMed: 28174757
  • Wang XQ & Dostie J Reciprocal regulation of chromatin state and architecture by HOTAIRM1 contributes to temporal collinear HOXA gene activation. Nucleic Acids Res 45:1091-1104 (2017). ChIP ; Human . PubMed: 28180285
  • Nguyen K  et al. Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency. MBio 8:N/A (2017). ChIP, WB ; Human . PubMed: 28246360
  • Du Y  et al. Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment. Cell Death Differ 24:1121-1131 (2017). CHIPseq ; Human . PubMed: 28475175
  • Ridings-Figueroa R  et al. The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory. Genes Dev 31:876-888 (2017). ICC/IF ; Mouse . PubMed: 28546514
  • Kim ED  et al. Spatio-temporal analysis of coding and long noncoding transcripts during maize endosperm development. Sci Rep 7:3838 (2017). ChIP . PubMed: 28630499
  • Halaburková A  et al. Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A. Clin Epigenetics 9:62 (2017). ChIP ; Human . PubMed: 28603560
  • Jensen GS  et al. The RNA Polymerase-Associated Factor 1 Complex Is Required for Plant Touch Responses. J Exp Bot 68:499-511 (2017). WB . PubMed: 28204553
  • Singh-Taylor A  et al. NRSF-dependent epigenetic mechanisms contribute to programming of stress-sensitive neurons by neonatal experience, promoting resilience. Mol Psychiatry N/A:N/A (2017). ChIP . PubMed: 28070121
  • Jung J  et al. Nicotinamide metabolism regulates glioblastoma stem cell maintenance. JCI Insight 2:N/A (2017). PubMed: 28515364
  • Wang Y  et al. Ezh2 Acts as a Tumor Suppressor in Kras-driven Lung Adenocarcinoma. Int J Biol Sci 13:652-659 (2017). PubMed: 28539837
  • Willi M  et al. Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells. Nat Commun 8:16069 (2017). PubMed: 28714474
  • Steiner LA  et al. CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells. PLoS One 11:e0155378 (2016). ChIP . PubMed: 27219007
  • Vaidya H  et al. Inactivation of the WNT5A Alternative Promoter B Is Associated with DNA Methylation and Histone Modification in Osteosarcoma Cell Lines U2OS and SaOS-2. PLoS One 11:e0151392 (2016). ChIP . PubMed: 26978652
  • Zhang ZZ  et al. Long non-coding RNA LINC00628 functions as a gastric cancer suppressor via long-range modulating the expression of cell cycle related genes. Sci Rep 6:27435 (2016). ChIP . PubMed: 27272474
  • Elnfati AH  et al. Nucleosomal chromatin in the mature sperm of Drosophila melanogaster. Genom Data 7:175-7 (2016). PubMed: 26981400
  • Zhang X  et al. Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes. PLoS One 11:e0150175 (2016). WB . PubMed: 26918332
  • Saayman SM  et al. Long Non-coding RNA BGas Regulates the Cystic Fibrosis Transmembrane Conductance Regulator. Mol Ther 24:1351-7 (2016). PubMed: 27434588
  • Gong C  et al. BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer. Oncogenesis 5:e214 (2016). ChIP . PubMed: 27043660
  • Li D  et al. Profiling Analysis of Histone Modifications and Gene Expression in Lewis Lung Carcinoma Murine Cells Resistant to Anti-VEGF Treatment. PLoS One 11:e0158214 (2016). ChIP . PubMed: 27362259
  • Liu Y  et al. Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells. Nat Commun 7:11275 (2016). ChIP . PubMed: 27117588
  • Shi H  et al. ASXL1 plays an important role in erythropoiesis. Sci Rep 6:28789 (2016). ChIP . PubMed: 27352931
  • Wang W  et al. PDX1 and ISL1 differentially coordinate with epigenetic modifications to regulate insulin gene expression in varied glucose concentrations. Mol Cell Endocrinol 428:38-48 (2016). PubMed: 26994512
  • Rius SP  et al. P1 Epigenetic Regulation in Leaves of High Altitude Maize Landraces: Effect of UV-B Radiation. Front Plant Sci 7:523 (2016). ChIP . PubMed: 27148340
  • Douvaras P  et al. Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes. Int J Mol Sci 17:N/A (2016). WB . PubMed: 27110779
  • Mendiratta S  et al. Interaction of the Chromatin Remodeling Protein hINO80 with DNA. PLoS One 11:e0159370 (2016). Human . PubMed: 27428271
  • Boija A & Mannervik M Initiation of diverse epigenetic states during nuclear programming of the Drosophila body plan. Proc Natl Acad Sci U S A 113:8735-40 (2016). PubMed: 27439862
  • Nandakumar V  et al. Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells. Sci Rep 6:30593 (2016). ICC/IF ; Human . PubMed: 27503568
  • Chen Y  et al. Suppression of PDCD4 mediated by the long non-coding RNA HOTAIR inhibits the proliferation and invasion of glioma cells. Oncol Lett 12:5170-5176 (2016). ChIP ; Human . PubMed: 28105224
  • Katsushima K  et al. Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment. Nat Commun 7:13616 (2016). ChIP ; Human . PubMed: 27922002
  • Yapp C  et al. H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis. Arthritis Res Ther 18:158 (2016). ICC/IF ; Human . PubMed: 27388528
  • Venkatesh I  et al. Epigenetic profiling reveals a developmental decrease in promoter accessibility during cortical maturation in vivo. Neuroepigenetics 8:19-26 (2016). ChIP ; Mouse . PubMed: 27990351
  • Heo SJ  et al. Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity. Elife 5:N/A (2016). ICC/IF ; Cow . PubMed: 27901466
  • Luizon MR  et al. Genomic Characterization of Metformin Hepatic Response. PLoS Genet 12:e1006449 (2016). CHIPseq ; Human . PubMed: 27902686
  • Zhao E  et al. Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Nat Immunol 17:95-103 (2016). ChIP ; Human . PubMed: 26523864
  • Navarro-Costa P  et al. Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling. Nat Commun 7:12331 (2016). IF ; Drosophila melanogaster . PubMed: 27507044
  • Wani AH  et al. Chromatin topology is coupled to Polycomb group protein subnuclear organization. Nat Commun 7:10291 (2016). ChIP ; Drosophila melanogaster . PubMed: 26759081
  • Veith N  et al. Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines. BMC Biotechnol 16:6 (2016). ChIP . PubMed: 26800878
  • Monte E  et al. Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. J Biol Chem 291:15428-46 (2016). WB ; Human . PubMed: 27226577
  • McKnight RA  et al. Intrauterine growth restriction inhibits expression of eukaryotic elongation factor 2 kinase, a regulator of protein translation. Physiol Genomics 48:616-25 (2016). ChIP ; Rat . PubMed: 27317589
  • Park SJ  et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene 35:1292-301 (2016). ChIP ; Human . PubMed: 26028027
  • Ancelin K  et al. Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. Elife 5:N/A (2016). IF . PubMed: 26836306
  • Wang XQ & Dostie J Reciprocal regulation of chromatin state and architecture by HOTAIRM1 contributes to temporal collinear HOXA gene activation. Nucleic Acids Res N/A:N/A (2016). ChIP ; Human . PubMed: 27789700
  • Nagarsheth N  et al. PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. Cancer Res 76:275-82 (2016). ChIP . PubMed: 26567139
  • Xia N  et al. SENP1 Is a Crucial Regulator for Cell Senescence through DeSUMOylation of Bmi1. Sci Rep 6:34099 (2016). PubMed: 27659494
  • Ye Y  et al. Chromatin remodeling during the in vivo glial differentiation in early Drosophila embryos. Sci Rep 6:33422 (2016). ChIP . PubMed: 27634414
  • Shih HT  et al. dBRWD3 Regulates Tissue Overgrowth and Ectopic Gene Expression Caused by Polycomb Group Mutations. PLoS Genet 12:e1006262 (2016). ChIP ; Drosophila melanogaster . PubMed: 27588417
  • Xu C  et al. MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA. Oncotarget 7:77764-77776 (2016). ChIP ; Human . PubMed: 27780918
  • Rando G  et al. Glucocorticoid receptor-PPARa axis in fetal mouse liver prepares neonates for milk lipid catabolism. Elife 5:N/A (2016). ChIP . PubMed: 27367842
  • Wani S  et al. Human SCP4 is a chromatin-associated CTD phosphatase and exhibits the dynamic translocation during erythroid differentiation. J Biochem 160:111-20 (2016). PubMed: 26920047
  • Huang X  et al. Imprinted gene OsFIE1 modulates rice seed development by influencing nutrient metabolism and modifying genome H3K27me3. Plant J 87:305-17 (2016). PubMed: 27133784
  • Ray MK  et al. CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development. J Biol Chem 291:19558-72 (2016). PubMed: 27405765
  • Wang H  et al. Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells. Sci Rep 6:27256 (2016). ICC/IF ; Pig . PubMed: 27264660
  • Meng S  et al. Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation. Circ Res 119:e129-e138 (2016). PubMed: 27623813
  • Meredith EK  et al. An RNA matchmaker protein regulates the activity of the long noncoding RNA HOTAIR. RNA 22:995-1010 (2016). PubMed: 27146324
  • Ueno K  et al. Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation. Sci Rep 6:29264 (2016). ChIP . PubMed: 27377164
  • Akhade VS  et al. Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells. Nucleic Acids Res 44:387-401 (2016). PubMed: 26446991
  • Erokhin M  et al. Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements. Proc Natl Acad Sci U S A 112:14930-5 (2015). ChIP ; Drosophila melanogaster . PubMed: 26504232
  • Sekiya T  et al. Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells. J Exp Med 212:1623-40 (2015). ChIP ; Mouse . PubMed: 26304965
  • McNeal AS  et al. CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma. Cancer Discov 5:1072-85 (2015). ChIP . PubMed: 26183406
  • Fukasawa R  et al. Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation. J Biochem 158:373-84 (2015). PubMed: 26002960
  • Kozono D  et al. Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression. Proc Natl Acad Sci U S A 112:E4055-64 (2015). ChIP ; Mouse . PubMed: 26159421
  • Tripathy MK  et al. H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells. J Virol 89:8392-405 (2015). PubMed: 26041287
  • Grasso CS  et al. Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nat Med 21:555-9 (2015). WB ; Human . PubMed: 25939062
  • Van der Meulen J  et al. The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia. Blood 125:13-21 (2015). PubMed: 25320243
  • Zhang W  et al. Pluripotent and Metabolic Features of Two Types of Porcine iPSCs Derived from Defined Mouse and Human ES Cell Culture Conditions. PLoS One 10:e0124562 (2015). ICC ; Pig . PubMed: 25893435
  • Kang SC  et al. Transcriptomic Profiling and H3K27me3 Distribution Reveal Both Demethylase-Dependent and Independent Regulation of Developmental Gene Transcription in Cell Differentiation. PLoS One 10:e0135276 (2015). WB ; Human . PubMed: 26263556
  • Schertel C  et al. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Genome Res 25:514-23 (2015). Drosophila melanogaster . PubMed: 25568052
  • Xiao X  et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun 6:8266 (2015). ChIP ; Mouse . PubMed: 26365427
  • Sperber H  et al. The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nat Cell Biol 17:1523-35 (2015). WB ; Human . PubMed: 26571212
  • Vandamme J  et al. H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans. Nucleic Acids Res 43:9694-710 (2015). IF ; Caenorhabditis elegans . PubMed: 26476455
  • Garruss AS & Fowler T Dataset of transcriptional landscape of B cell early activation. Genom Data 5:238-40 (2015). CHIPseq ; Mouse . PubMed: 26484262
  • Hatanaka Y  et al. Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons. Proc Natl Acad Sci U S A 112:14641-6 (2015). ChIP, ICC/IF ; Mouse . PubMed: 26546670
  • Philip P  et al. CBP binding outside of promoters and enhancers in Drosophila melanogaster. Epigenetics Chromatin 8:48 (2015). Drosophila melanogaster . PubMed: 26604986
  • Geeven G  et al. Local compartment changes and regulatory landscape alterations in histone H1-depleted cells. Genome Biol 16:289 (2015). CHIPseq ; Mouse . PubMed: 26700097
  • Fowler T  et al. Divergence of transcriptional landscape occurs early in B cell activation. Epigenetics Chromatin 8:20 (2015). CHIPseq . PubMed: 25987903
  • Karamitros D  et al. Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development 142:70-81 (2015). ChIP ; Human . PubMed: 25516969
  • Zhang H  et al. PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis. Cancer Res 75:2363-74 (2015). ChIP . PubMed: 25855382
  • Sun C  et al. Epigenetic regulation of histone modifications and Gata6 gene expression induced by maternal diet in mouse embryoid bodies in a model of developmental programming. BMC Dev Biol 15:3 (2015). ChIP ; Mouse . PubMed: 25609498
  • Balasubramani A  et al. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nat Commun 6:7307 (2015). ICC ; Mouse . PubMed: 26095772
  • Maekawa S  et al. Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance. BMC Genomics 16:154 (2015). ChIP ; Human . PubMed: 25879614
  • Singh AM  et al. Cell-Cycle Control of Bivalent Epigenetic Domains Regulates the Exit from Pluripotency. Stem Cell Reports 5:323-36 (2015). ChIP ; Human . PubMed: 26278042
  • Yao X  et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J 34:2885-902 (2015). WB . PubMed: 26330467
  • LaFave LM  et al. Loss of BAP1 function leads to EZH2-dependent transformation. Nat Med 21:1344-9 (2015). WB, ChIP . PubMed: 26437366
  • Wurm S  et al. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes Dev 29:144-56 (2015). ChIP ; Mouse . PubMed: 25547114
  • Müller-Kuller U  et al. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells. Nucleic Acids Res 43:1577-92 (2015). ChIP . PubMed: 25605798
  • Navarro JM  et al. Site- and allele-specific polycomb dysregulation in T-cell leukaemia. Nat Commun 6:6094 (2015). ChIP . PubMed: 25615415
  • Koo JW  et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci 18:415-22 (2015). ChIP ; Rat . PubMed: 25643298
  • Xiao T  et al. Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPa. Stem Cell Reports 5:856-65 (2015). ChIP ; Human . PubMed: 26489893
  • Liu C  et al. PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex. Nucleic Acids Res 43:6270-84 (2015). WB ; Human . PubMed: 26038315
  • Sahu SK  et al. JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J 34:2162-81 (2015). ChIP ; Mouse . PubMed: 26157010
  • Tran PV  et al. Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus. Am J Physiol Regul Integr Comp Physiol 308:R276-82 (2015). ChIP ; Rat . PubMed: 25519736
  • Fufa TD  et al. Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes. Hum Mol Genet 24:5433-50 (2015). ChIP ; Mouse . PubMed: 26206884
  • Kassab MA  et al. Gene Silencing and Activation of Human Papillomavirus 18 Is Modulated by Sense Promoter Associated RNA in Bidirectionally Transcribed Long Control Region. PLoS One 10:e0128416 (2015). ChIP ; Human . PubMed: 26047143
  • Porter LF  et al. A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome. Hum Mol Genet 24:6565-79 (2015). WB ; Human . PubMed: 26395458
  • Rothbart SB  et al. An Interactive Database for the Assessment of Histone Antibody Specificity. Mol Cell 59:502-11 (2015). ChIP ; Mouse . PubMed: 26212453
  • Wan J  et al. PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression. Nucleic Acids Res 43:3591-604 (2015). WB ; Human . PubMed: 25800736
  • Nordström L  et al. DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells. BMC Cancer 15:273 (2015). ChIP ; Human . PubMed: 25880212
  • Guo Z  et al. Global epigenomic analysis indicates that epialleles contribute to Allele-specific expression via Allele-specific histone modifications in hybrid rice. BMC Genomics 16:232 (2015). CHIPseq ; Rice . PubMed: 25886904
  • Xu G  et al. The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor a (TNF-a) production. J Biol Chem 290:5414-23 (2015). ChIP ; Mouse . PubMed: 25583990
  • Liu Y  et al. Histone lysine methyltransferase Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing Tollip. J Immunol 194:2838-46 (2015). IP ; Mouse . PubMed: 25687760
  • Cook KD  et al. T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX. Immunity 43:703-14 (2015). PubMed: 26431949
  • Li Q  et al. KDM6B induces epithelial-mesenchymal transition and enhances clear cell renal cell carcinoma metastasis through the activation of SLUG. Int J Clin Exp Pathol 8:6334-44 (2015). PubMed: 26261509
  • Lu S  et al. The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2. Oncotarget 6:34704-17 (2015). WB . PubMed: 26430963
  • Vlachogiannis G  et al. The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis. Cell Rep N/A:N/A (2015). PubMed: 25683717
  • Reeder JE  et al. HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells. Elife 4:N/A (2015). ChIP . PubMed: 26488441
  • Erfani P  et al. EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas. Epigenetics 10:496-507 (2015). PubMed: 25996283
  • Wei FZ  et al. Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway. Autophagy 11:2309-22 (2015). PubMed: 26735435
  • Liao MY  et al. Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer. Int J Oncol 46:1788-800 (2015). PubMed: 25652097
  • Takayama K  et al. RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer. Oncotarget 6:2263-76 (2015). PubMed: 25537508
  • Ehrensberger AH  et al. Retention of the Native Epigenome in Purified Mammalian Chromatin. PLoS One 10:e0133246 (2015). ChIP . PubMed: 26248330
  • Lybæk H  et al. RevSex duplication-induced and sex-related differences in the SOX9 regulatory region chromatin landscape in human fibroblasts. Epigenetics 9:416-27 (2014). ChIP . PubMed: 24351654
  • Whitworth DJ  et al. Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells Dev 23:1515-23 (2014). PubMed: 24555755
  • Jiang Y  et al. Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion. Stem Cells Dev 23:2283-96 (2014). PubMed: 24805295
  • Harms MJ  et al. Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab 19:593-604 (2014). PubMed: 24703692
  • Izzo F  et al. Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. Breast Cancer Res 16:491 (2014). PubMed: 25479686
  • Himeda CL  et al. Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene. Mol Cell Biol 34:1942-55 (2014). PubMed: 24636994
  • Walsh CA  et al. Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis. Cancer Res 74:2533-44 (2014). PubMed: 24648347
  • Whitworth DJ  et al. Derivation of mesenchymal stromal cells from canine induced pluripotent stem cells by inhibition of the TGFß/activin signaling pathway. Stem Cells Dev 23:3021-33 (2014). ICC . PubMed: 25055193
  • Sequeira-Mendes J  et al. The Functional Topography of the Arabidopsis Genome Is Organized in a Reduced Number of Linear Motifs of Chromatin States. Plant Cell 26:2351-2366 (2014). ChIP/Chip ; Arabidopsis thaliana . PubMed: 24934173
  • Deneberg S  et al. microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia. Epigenetics 9:910-7 (2014). PubMed: 24686393
  • Ahsan S  et al. Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma. Acta Neuropathol Commun 2:59 (2014). IHC . PubMed: 24894482
  • Benard A  et al. Chromatin status of apoptosis genes correlates with sensitivity to chemo-, immune- and radiation therapy in colorectal cancer cell lines. Apoptosis 19:1769-78 (2014). PubMed: 25292014
  • Song G  et al. The phenotypic predisposition of the parent in F1 hybrid is correlated with transcriptome preference of the positive general combining ability parent. BMC Genomics 15:297 (2014). ChIP . PubMed: 24755044
  • Zhu X  et al. Identification of functional cooperative mutations of SETD2 in human acute leukemia. Nat Genet 46:287-93 (2014). PubMed: 24509477
  • Shen H  et al. BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. J Cell Mol Med 18:1004-17 (2014). ChIP . PubMed: 24571310
  • Mak KS  et al. Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor. Genome Biol 15:R58 (2014). ChIP ; Mouse . PubMed: 24946810
  • Yamamoto K  et al. Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPa. Carcinogenesis 35:2404-14 (2014). WB ; Human . PubMed: 24947179
  • Kumari D & Usdin K Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription. Hum Mol Genet 23:6575-83 (2014). ChIP . PubMed: 25055869
  • Siegle JM  et al. SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma. Nat Commun 5:4511 (2014). ChIP . PubMed: 25077433
  • Ullius A  et al. The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification. Nucleic Acids Res : (2014). PubMed: 24782528
  • Creppe C  et al. A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation. PLoS Genet 10:e1004851 (2014). PubMed: 25500566
  • Horrell SA & Chalker DL LIA4 encodes a chromoshadow domain protein required for genomewide DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell 13:1300-11 (2014). PubMed: 25084866
  • Suzuki A  et al. Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines. Nucleic Acids Res 42:13557-72 (2014). CHIPseq ; Human . PubMed: 25378332
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