Overview

  • Product nameHistone H3 (tri-methyl K27) Assay Kit
    See all Histone H3 (K27 methylation) kits
  • Tests
    1 x 48 test
  • Sample type
    Tissue, Adherent cells, Suspension cells
  • Assay typeQuantitative
  • Assay time
    5h 00m
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: all Mammals
  • Product overview

    Methylation of histone H3 at lysine 27 has an important role in transcription repression and it is catalyzed by G9a and Polycomb Groups enzymes such as EZH2. In particular, tri-methylation of histone H3 at lysine 27 (H3 (tri-methyl K27)) is a facultative heterochromatin mark, which promotes the recruitment of polycomb group proteins for gene silencing. Increased global histone H3 (tri-methyl K27) is also found to be involved in some pathological processes such as cancer progression.

    Abcam's Histone H3 (tri-methyl K27) Assay Kit (ab115051) is suitable for specifically measuring global histone H3K27 tri-methylation using a variety of mammalian cells including fresh and frozen tissues, cultured adherent and suspension cells.

  • Tested applicationsSuitable for: Functional Studiesmore details

Properties

    Applications

    Our Abpromise guarantee covers the use of ab115051 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Functional Studies Use at an assay dependent concentration.

    Protocols

    References for Histone H3 (tri-methyl K27) Assay Kit (ab115051)

    ab115051 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab115051.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"