Anti-Histone H3 (tri methyl K9) antibody - ChIP Grade (ab8898)

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ab8898 has been referenced in 506 publications.

  • Gursoy-Yuzugullu O  et al. Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity. Oncotarget 8:24518-24532 (2017). WB ; Human . PubMed: 28445939
  • Yang G  et al. The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction. Nat Commun 8:14941 (2017). ChIP . PubMed: 28361889
  • Gómez-Díaz E  et al. Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae. Sci Rep 7:40655 (2017). CHIPseq ; Plasmodium falciparum . PubMed: 28091569
  • Xu J  et al. Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells. Nat Genet 49:377-386 (2017). ChIP ; Mouse . PubMed: 28112738
  • Altieri F  et al. Epigenetic alterations of gastrokine 1 gene expression in gastric cancer. Oncotarget 8:16899-16911 (2017). WB, ChIP ; Human . PubMed: 28129645
  • Chen S  et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res 45:1144-1158 (2017). WB ; Human . PubMed: 28180298
  • Guitart AV  et al. Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions. J Exp Med 214:719-735 (2017). WB ; Mouse . PubMed: 28202494
  • Amendola PG  et al. JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity. PLoS Genet 13:e1006632 (2017). WB ; Caenorhabditis elegans . PubMed: 28207814
  • Yang WS  et al. SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication. PLoS Pathog 13:e1006216 (2017). WB, ICC/IF, CHIPseq ; Human . PubMed: 28212444
  • Nguyen K  et al. Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency. MBio 8:N/A (2017). ChIP ; Human . PubMed: 28246360
  • Kidder BL  et al. SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation. Epigenetics Chromatin 10:8 (2017). CHIPseq ; Mouse . PubMed: 28250819
  • Liu K  et al. DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells. PLoS One 12:e0173047 (2017). WB ; Pig . PubMed: 28253351
  • Tumber A  et al. Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. Cell Chem Biol 24:371-380 (2017). ICC/IF ; Human . PubMed: 28262558
  • Cleven AHG  et al. IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas. Clin Sarcoma Res 7:8 (2017). IHC ; Human . PubMed: 28484589
  • Magaraki A  et al. Silencing markers are retained on pericentric heterochromatin during murine primordial germ cell development. Epigenetics Chromatin 10:11 (2017). IF ; Mouse . PubMed: 28293300
  • Salzberg AC  et al. Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability. PLoS One 12:e0173723 (2017). WB, ChIP ; Human . PubMed: 28301528
  • Torres-Guzmán R  et al. Preclinical characterization of abemaciclib in hormone receptor positive breast cancer. Oncotarget N/A:N/A (2017). PubMed: 28537883
  • Huo Q  et al. Dysfunction of IKZF1/MYC/MDIG axis contributes to liver cancer progression through regulating H3K9me3/p21 activity. Cell Death Dis 8:e2766 (2017). WB ; Human . PubMed: 28471446
  • Gan X  et al. Epigenetically repressing human cytomegalovirus lytic infection and reactivation from latency in THP-1 model by targeting H3K9 and H3K27 histone demethylases. PLoS One 12:e0175390 (2017). PubMed: 28407004
  • Walsh RM  et al. Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice. Nat Commun 8:15142 (2017). WB ; Mouse . PubMed: 28485378
  • Wan J  et al. Methylated cis-regulatory elements mediate KLF4-dependent gene transactivation and cell migration. Elife 6:N/A (2017). ChIP ; Human . PubMed: 28553926
  • Hewitson TD  et al. Epigenetic Modifications to H3K9 in Renal Tubulointerstitial Cells after Unilateral Ureteric Obstruction and TGF-ß1 Stimulation. Front Pharmacol 8:307 (2017). WB, ICC/IF ; Mouse . PubMed: 28611663
  • Esanov R  et al. A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD. Mol Neurodegener 12:46 (2017). ChIP ; Mouse . PubMed: 28606110
  • Cheng W  et al. Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells. Cell Death Dis 8:e2628 (2017). Human . PubMed: 28230864
  • Roy S & Sridharan R Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes. Genome Res 27:1250-1262 (2017). ChIP/Chip . PubMed: 28424352
  • Li Y  et al. Vitamin C alleviates aging defects in a stem cell model for Werner syndrome. Protein Cell 7:478-88 (2016). WB ; Human . PubMed: 27271327
  • Park SJ  et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene 35:1292-301 (2016). ChIP ; Human . PubMed: 26028027
  • Yuan L  et al. A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity. Nat Commun 7:10160 (2016). ChIP ; Human . PubMed: 26744078
  • Spagnol ST & Dahl KN Spatially Resolved Quantification of Chromatin Condensation through Differential Local Rheology in Cell Nuclei Fluorescence Lifetime Imaging. PLoS One 11:e0146244 (2016). IHC-P ; Human . PubMed: 26765322
  • Veith N  et al. Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines. BMC Biotechnol 16:6 (2016). ChIP . PubMed: 26800878
  • Timms RT  et al. ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex. Cell Rep 17:653-659 (2016). CHIPseq ; Human . PubMed: 27732843
  • Su Z  et al. Reader domain specificity and lysine demethylase-4 family function. Nat Commun 7:13387 (2016). WB ; Mouse . PubMed: 27841353
  • Zhang Q  et al. Tcstv1 and Tcstv3 elongate telomeres of mouse ES cells. Sci Rep 6:19852 (2016). WB ; Mouse . PubMed: 26816107
  • Schiavone D  et al. PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells. Mol Cell 61:161-9 (2016). ChIP ; Chicken . PubMed: 26626482
  • Gómez R  et al. Male meiosis in Crustacea: synapsis, recombination, epigenetics and fertility in Daphnia magna. Chromosoma 125:769-87 (2016). ICC/IF . PubMed: 26685998
  • Zhang H  et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS One 11:e0167454 (2016). WB, ICC/IF ; Human . PubMed: 27907109
  • Bieberstein NI  et al. TALE-directed local modulation of H3K9 methylation shapes exon recognition. Sci Rep 6:29961 (2016). ChIP . PubMed: 27439481
  • Boija A & Mannervik M Initiation of diverse epigenetic states during nuclear programming of the Drosophila body plan. Proc Natl Acad Sci U S A 113:8735-40 (2016). PubMed: 27439862
  • Nandakumar V  et al. Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells. Sci Rep 6:30593 (2016). WB, ICC/IF ; Human . PubMed: 27503568
  • Baude A  et al. Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination. Nucleic Acids Res 44:2214-26 (2016). ICC/IF ; Human . PubMed: 26721387
  • Luo Z  et al. Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity. Genes Dev 30:92-101 (2016). Mouse . PubMed: 26728555
  • Diaferia GR  et al. Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer. EMBO J 35:595-617 (2016). CHIPseq ; Human . PubMed: 26769127
  • Molina O  et al. PREditOR: a synthetic biology approach to removing heterochromatin from cells. Chromosome Res 24:495-509 (2016). ICC/IF ; Human . PubMed: 27924426
  • Cisneros-Soberanis F  et al. miR-125b-1 is repressed by histone modifications in breast cancer cell lines. Springerplus 5:959 (2016). ChIP ; Human . PubMed: 27386402
  • Vento-Tormo R  et al. IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation. Genome Biol 17:4 (2016). ChIP . PubMed: 26758199
  • Franklin S  et al. The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. Am J Physiol Heart Circ Physiol 311:H1234-H1247 (2016). PubMed: 27663768
  • Federici F  et al. Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse. PLoS Genet 12:e1006358 (2016). ICC/IF ; Mouse . PubMed: 27716834
  • Erwin GS  et al. Synthetic genome readers target clustered binding sites across diverse chromatin states. Proc Natl Acad Sci U S A 113:E7418-E7427 (2016). PubMed: 27830652
  • Fukuda A  et al. Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice. PLoS Genet 12:e1006375 (2016). ICC/IF ; Mouse . PubMed: 27788132
  • Chen S  et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res N/A:N/A (2016). WB ; Human . PubMed: 27789696
  • Guerreiro I  et al. Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife 5:N/A (2016). ChIP . PubMed: 27476854
  • Sun H  et al. Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch. Sci Rep 6:30903 (2016). WB . PubMed: 27481483
  • Teperek M  et al. Sperm is epigenetically programmed to regulate gene transcription in embryos. Genome Res 26:1034-46 (2016). CHIPseq ; Xenopus laevis . PubMed: 27034506
  • Rando G  et al. Glucocorticoid receptor-PPARa axis in fetal mouse liver prepares neonates for milk lipid catabolism. Elife 5:N/A (2016). ChIP . PubMed: 27367842
  • Nelson DM  et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol 17:158 (2016). IHC-P ; Human . PubMed: 27457071
  • Hossain M & Stillman B Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription. Elife 5:N/A (2016). ChIP ; Human . PubMed: 27458800
  • Tong D  et al. The HIF/PHF8/AR axis promotes prostate cancer progression. Oncogenesis 5:e283 (2016). Human . PubMed: 27991916
  • Fneich S  et al. Epigenetic origin of adaptive phenotypic variants in the human blood fluke Schistosoma mansoni. Epigenetics Chromatin 9:27 (2016). ChIP . PubMed: 27379173
  • Tsuchiya Y  et al. ThPOK represses CXXC5, which induces methylation of histone H3 lysine 9 in Cd40lg promoter by association with SUV39H1: implications in repression of CD40L expression in CD8+ cytotoxic T cells. J Leukoc Biol 100:327-38 (2016). PubMed: 26896487
  • Fukuda A  et al. Spatiotemporal dynamics of OCT4 protein localization during preimplantation development in mice. Reproduction 152:417-30 (2016). ICC/IF ; Mouse . PubMed: 27495230
  • Amabile A  et al. Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing. Cell 167:219-232.e14 (2016). ChIP . PubMed: 27662090
  • Wang LY  et al. KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis. Cell Rep 16:3016-27 (2016). PubMed: 27626669
  • Perovanovic J  et al. Laminopathies disrupt epigenomic developmental programs and cell fate. Sci Transl Med 8:335ra58 (2016). ChIP . PubMed: 27099177
  • Lutz L  et al. Histone modifiers and marks define heterogeneous groups of colorectal carcinomas and affect responses to HDAC inhibitors in vitro. Am J Cancer Res 6:664-76 (2016). IHC-P ; Human . PubMed: 27152243
  • Takikita S  et al. A Histone Methyltransferase ESET Is Critical for T Cell Development. J Immunol 197:2269-79 (2016). ChIP . PubMed: 27511731
  • Chen T  et al. Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7. Front Mol Neurosci 9:94 (2016). ChIP . PubMed: 27752241
  • Ho SC  et al. Evaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells. BMC Biotechnol 16:71 (2016). IP . PubMed: 27756290
  • Shan CM  et al. A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading. Elife 5:N/A (2016). ChIP . PubMed: 27648579
  • Kramer HB  et al. LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner. Nucleic Acids Res 44:582-94 (2016). ChIP ; Human . PubMed: 26400164
  • Liu J  et al. Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice. J Neurosci 36:957-62 (2016). PubMed: 26791223
  • Valle-García D  et al. ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment. Epigenetics N/A:0 (2016). ChIP, CHIPseq . PubMed: 27029610
  • Ni JZ  et al. A transgenerational role of the germline nuclear RNAi pathway in repressing heat stress-induced transcriptional activation in C. elegans. Epigenetics Chromatin 9:3 (2016). WB, ChIP, CHIPseq ; Caenorhabditis elegans . PubMed: 26779286
  • Breaux M  et al. p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways. Mol Cell Biol 35:3005-16 (2015). PubMed: 26100016
  • Maeng YS  et al. Histone methylation levels correlate with TGFBIp and extracellular matrix gene expression in normal and granular corneal dystrophy type 2 corneal fibroblasts. BMC Med Genomics 8:74 (2015). Human . PubMed: 26553048
  • Oh HS  et al. Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters. MBio 6:e00345-15 (2015). ChIP, ICC/IF ; Human . PubMed: 26015494
  • Ma S  et al. D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth. Oncotarget 6:8606-20 (2015). PubMed: 25825982
  • Mauger O  et al. Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions. Nucleic Acids Res 43:1869-82 (2015). WB . PubMed: 25605796
  • McNeal AS  et al. CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma. Cancer Discov 5:1072-85 (2015). ChIP . PubMed: 26183406
  • Konno M  et al. Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming. PLoS One 10:e0132789 (2015). ChIP ; Mouse . PubMed: 26176628
  • Nizialek EA  et al. Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability. Nucleic Acids Res : (2015). WB, ChIP ; Human . PubMed: 26673699
  • Mugat B  et al. MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells. PLoS Genet 11:e1005194 (2015). ChIP ; Drosophila melanogaster . PubMed: 25993106
  • Herberg S  et al. Histone H3 lysine 9 trimethylation is required for suppressing the expression of an embryonically activated retrotransposon in Xenopus laevis. Sci Rep 5:14236 (2015). ChIP ; Xenopus laevis . PubMed: 26387861
  • Schliehe C  et al. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nat Immunol 16:67-74 (2015). ChIP ; Mouse . PubMed: 25419628
  • Riffo-Campos ÁL  et al. Nucleosome-specific, time-dependent changes in histone modifications during activation of the early growth response 1 (Egr1) gene. J Biol Chem 290:197-208 (2015). ChIP ; Mouse . PubMed: 25378406
  • Kernytsky A  et al. IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition. Blood 125:296-303 (2015). WB . PubMed: 25398940
  • Sanz-Moreno A  et al. Late onset neuropathy with spontaneous clinical remission in mice lacking the POZ domain of the transcription factor Myc-interacting zinc finger protein 1 (Miz1) in Schwann cells. J Biol Chem 290:727-43 (2015). IHC-P ; Mouse . PubMed: 25416780
  • Zhou Q & Bachtrog D Ancestral Chromatin Configuration Constrains Chromatin Evolution on Differentiating Sex Chromosomes in Drosophila. PLoS Genet 11:e1005331 (2015). PubMed: 26114585
  • Harr JC  et al. Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins. J Cell Biol 208:33-52 (2015). IF ; Mouse . PubMed: 25559185
  • Wang C  et al. IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma. Blood 126:1741-52 (2015). PubMed: 26268241
  • Rolyan H  et al. Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. J Neurosci 35:12002-17 (2015). Mouse . PubMed: 26311780
  • Heubach J  et al. The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells. Mol Cancer 14:108 (2015). ChIP ; Human . PubMed: 25994132
  • Jang CW  et al. Histone H3.3 maintains genome integrity during mammalian development. Genes Dev 29:1377-92 (2015). WB . PubMed: 26159997
  • Vento-Tormo R  et al. Gains of DNA methylation in myeloid terminal differentiation are dispensable for gene silencing but influence the differentiated phenotype. FEBS J 282:1815-25 (2015). PubMed: 25219924
  • Carroll J  et al. Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing. Hum Mol Genet 24:828-40 (2015). WB ; Mouse . PubMed: 25274775
  • Doldi V  et al. Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation. Oncotarget 6:31441-60 (2015). ICC/IF ; Human . PubMed: 26375444
  • Victoria-Acosta G  et al. Epigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding. Sci Rep 5:14838 (2015). ChIP ; Human . PubMed: 26443201
  • Guo J  et al. Identification and Epigenetic Analysis of a Maternally Imprinted Gene Qpct. Mol Cells 38:859-65 (2015). ChIP ; Mouse . PubMed: 26447138
  • Fukuda A  et al. Chromatin condensation of Xist genomic loci during oogenesis in mice. Development 142:4049-55 (2015). ChIP, ICC/IF ; Mouse . PubMed: 26459223
  • Papadopoulou C  et al. Nucleotide Pool Depletion Induces G-Quadruplex-Dependent Perturbation of Gene Expression. Cell Rep 13:2491-503 (2015). ChIP ; Chicken . PubMed: 26686635
  • Liang S  et al. Scriptaid Treatment Decreases DNA Methyltransferase 1 Expression by Induction of MicroRNA-152 Expression in Porcine Somatic Cell Nuclear Transfer Embryos. PLoS One 10:e0134567 (2015). IHC-P ; Pig . PubMed: 26261994
  • Liu J  et al. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci 35:352-65 (2015). WB, IHC-Fr, ChIP . PubMed: 25568127
  • Zamudio N  et al. DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination. Genes Dev 29:1256-70 (2015). ChIP ; Mouse . PubMed: 26109049
  • Sperber H  et al. The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nat Cell Biol 17:1523-35 (2015). WB ; Human . PubMed: 26571212
  • Prakash K  et al. Superresolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes. Proc Natl Acad Sci U S A 112:14635-40 (2015). Mouse . PubMed: 26561583
  • Geeven G  et al. Local compartment changes and regulatory landscape alterations in histone H1-depleted cells. Genome Biol 16:289 (2015). CHIPseq ; Mouse . PubMed: 26700097
  • Jacob V  et al. DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos. Development 142:510-21 (2015). WB ; Zebrafish . PubMed: 25564650
  • Liao HF  et al. Dnmt3l-knockout donor cells improve somatic cell nuclear transfer reprogramming efficiency. Reproduction 150:245-56 (2015). WB ; Mouse . PubMed: 26159833
  • Jin Y  et al. Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes. PLoS One 10:e0131998 (2015). WB ; Human . PubMed: 26161668
  • Feliciello I  et al. Satellite DNA Modulates Gene Expression in the Beetle Tribolium castaneum after Heat Stress. PLoS Genet 11:e1005466 (2015). ChIP ; Tribolium castaneum . PubMed: 26275223
  • Udugama M  et al. Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres. Nucleic Acids Res 43:10227-37 (2015). Mouse . PubMed: 26304540
  • Roquis D  et al. The Epigenome of Schistosoma mansoni Provides Insight about How Cercariae Poise Transcription until Infection. PLoS Negl Trop Dis 9:e0003853 (2015). ChIP . PubMed: 26305466
  • Zhong F  et al. A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes. Nucleic Acids Res 43:10474-91 (2015). ChIP ; Mouse . PubMed: 26405199
  • Porter LF  et al. A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome. Hum Mol Genet 24:6565-79 (2015). WB ; Human . PubMed: 26395458
  • Liu CF & Lefebvre V The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis. Nucleic Acids Res 43:8183-203 (2015). ChIP ; Rat . PubMed: 26150426
  • Xiao T  et al. CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding Sites. Cell Rep 12:1704-14 (2015). PubMed: 26321640
  • Yao X  et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J 34:2885-902 (2015). WB . PubMed: 26330467
  • Pnueli L  et al. RNA transcribed from a distal enhancer is required for activating the chromatin at the promoter of the gonadotropin a-subunit gene. Proc Natl Acad Sci U S A 112:4369-74 (2015). ChIP ; Mouse . PubMed: 25810254
  • Wu C  et al. Modulation of Macrophage Gene Expression via Liver X Receptor a Serine 198 Phosphorylation. Mol Cell Biol 35:2024-34 (2015). ChIP ; Mouse, Human . PubMed: 25825525
  • Kim HJ  et al. Identification of a new selective chemical inhibitor of mutant isocitrate dehydrogenase-1. J Cancer Prev 20:78-83 (2015). WB ; Human . PubMed: 25853107
  • Wijchers PJ  et al. Characterization and dynamics of pericentromere-associated domains in mice. Genome Res 25:958-69 (2015). ChIP ; Mouse . PubMed: 25883320
  • Lowe R  et al. Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development. BMC Genomics 16:295 (2015). CHIPseq ; Mouse . PubMed: 25888192
  • Yoon KH  et al. Olfactory receptor genes expressed in distinct lineages are sequestered in different nuclear compartments. Proc Natl Acad Sci U S A 112:E2403-9 (2015). IHC ; Mouse . PubMed: 25897022
  • Jeong K  et al. Insulin-response epigenetic activation of Egr-1 and JunB genes at the nuclear periphery by A-type lamin-associated pY19-Caveolin-2 in the inner nuclear membrane. Nucleic Acids Res 43:3114-27 (2015). ICC/IF ; Rat . PubMed: 25753664
  • Ji X  et al. Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions. Proc Natl Acad Sci U S A 112:3841-6 (2015). WB, ChIP, CHIPseq ; Mouse . PubMed: 25755260
  • Brookes E  et al. Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity. Hum Mol Genet 24:2861-72 (2015). WB ; Human . PubMed: 25666439
  • Yang Q  et al. Mechanism of siRNA production from repetitive DNA. Genes Dev 29:526-37 (2015). ChIP ; Neurospora crassa . PubMed: 25691092
  • Dan J  et al. Roles for Histone Acetylation in Regulation of Telomere Elongation and Two-cell State in Mouse ES Cells. J Cell Physiol 230:2337-44 (2015). WB ; Mouse . PubMed: 25752831
  • Tarangelo A  et al. Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. Nat Commun 6:10028 (2015). ChIP ; Mouse . PubMed: 26639898
  • Hontelez S  et al. Embryonic transcription is controlled by maternally defined chromatin state. Nat Commun 6:10148 (2015). ChIP . PubMed: 26679111
  • Woo YM  et al. Epigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cyst growth in ADPKD. Sci Rep 5:15238 (2015). ChIP ; Human . PubMed: 26463459
  • Müller-Kuller U  et al. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells. Nucleic Acids Res 43:1577-92 (2015). ChIP . PubMed: 25605798
  • Sosa MS  et al. NR2F1 controls tumour cell dormancy via SOX9- and RARß-driven quiescence programmes. Nat Commun 6:6170 (2015). ChIP . PubMed: 25636082
  • Koo JW  et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci 18:415-22 (2015). ChIP ; Rat . PubMed: 25643298
  • Mayor R  et al. Genome distribution of replication-independent histone H1 variants shows H1.0 associated with nucleolar domains and H1X associated with RNA polymerase II-enriched regions. J Biol Chem 290:7474-91 (2015). WB ; Human . PubMed: 25645921
  • Mutonga M  et al. Targeting Suppressor of Variegation 3-9 Homologue 2 (SUV39H2) in Acute Lymphoblastic Leukemia (ALL). Transl Oncol 8:368-75 (2015). WB ; Human . PubMed: 26500027
  • Thakore PI  et al. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. Nat Methods 12:1143-9 (2015). ChIP ; Human . PubMed: 26501517
  • Peng D  et al. Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy. Nature 527:249-53 (2015). WB ; Human . PubMed: 26503055
  • Dou Z  et al. Autophagy mediates degradation of nuclear lamina. Nature 527:105-9 (2015). ICC/IF ; Human . PubMed: 26524528
  • Bitler BG  et al. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nat Med 21:231-8 (2015). WB, IHC . PubMed: 25686104
  • Bryant JM  et al. Characterization of BRD4 during mammalian postmeiotic sperm development. Mol Cell Biol 35:1433-48 (2015). ChIP ; Mouse . PubMed: 25691659
  • Gjoneska E  et al. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease. Nature 518:365-9 (2015). ChIP ; Mouse . PubMed: 25693568
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