Histone H4 (di-methyl K20) Quantification Kit (Colorimetric) (ab115095)

Overview

  • Product nameHistone H4 (di-methyl K20) Quantification Kit (Colorimetric)
    See all Histone H4 (K20 methylation) kits
  • Sensitivity
    5 ng/well
  • Range
    20 ng/well - 2000 ng/well
  • Assay time
    2h 30m
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: all Mammals
  • Product overview

    Methylation of histone H4 at lysine 20 is catalyzed by SET9 and SUV4.20h among other methyl transferases in mammalian cells. H4 (di-methyl K20) has been described as repressive chromatin domain and involved in DNA damage response.

    Histone H4 (di-methyl K20) Quantification Kit (Colorimetric) (ab115095) enables the user to measure global di-methylation of histone H4K20. The global H4K20 di-methylation can also be changed by inhibiton or activation of HMTs, making quantitative detection of global di-methyl histone H4K20 a useful tool for better understanding epigenetic regulation of gene activation/repression. ab115095 is suitable for use with a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.

  • Tested applicationsFunctional Studiesmore details

Properties

    Applications

    Our Abpromise guarantee covers the use of ab115095 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Functional Studies Use at an assay dependent concentration.

    Protocols

    References for Histone H4 (di-methyl K20) Quantification Kit (Colorimetric) (ab115095)

    ab115095 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"