Anti-Histone H4 (tri methyl K20) antibody - ChIP Grade (ab9053)

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ab9053 has been referenced in 78 publications.

  • Khan SA  et al. p38-MAPK/MSK1-mediated overexpression of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancer. Clin Epigenetics 8:88 (2016). PubMed: 27588146
  • Svensson JP  et al. A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin. Genome Res 25:872-83 (2015). ChIP ; Schizosaccharomyces pombe . PubMed: 25778913
  • Miotto B  et al. The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability. Cell Rep 7:575-87 (2014). WB . PubMed: 24726359
  • Klement K  et al. Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair. J Cell Biol 207:717-33 (2014). PubMed: 25533843
  • Thanisch K  et al. Targeting and tracing of specific DNA sequences with dTALEs in living cells. Nucleic Acids Res 42:e38 (2014). ICC/IF ; Human . PubMed: 24371265
  • Harding JL  et al. Small RNA profiling of Xenopus embryos reveals novel miRNAs and a new class of small RNAs derived from intronic transposable elements. Genome Res 24:96-106 (2014). ChIP ; Xenopus laevis, Xenopus tropicalis . PubMed: 24065776
  • Maroschik B  et al. Radiation-induced alterations of histone post-translational modification levels in lymphoblastoid cell lines. Radiat Oncol 9:15 (2014). WB ; Human . PubMed: 24406105
  • Vaskova EA  et al. Dynamics of the two heterochromatin types during imprinted X chromosome inactivation in vole Microtus levis. PLoS One 9:e88256 (2014). ICC/IF . PubMed: 24505450
  • Leung JW  et al. Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling. PLoS Genet 10:e1004178 (2014). WB ; Human . PubMed: 24603765
  • Kapoor-Vazirani P & Vertino PM A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. J Biol Chem 289:7425-37 (2014). ChIP ; Human . PubMed: 24459145
  • Lu P  et al. Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection. J Exp Med 211:515-27 (2014). PubMed: 24590765
  • Fulka H & Langerova A The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition. Development 141:1694-704 (2014). PubMed: 24715459
  • Perfus-Barbeoch L  et al. Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita. Front Physiol 5:211 (2014). WB . PubMed: 24936189
  • Blackledge NP  et al. Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation. Cell 157:1445-59 (2014). ChIP . PubMed: 24856970
  • Brahmachary M  et al. Digital genotyping of macrosatellites and multicopy genes reveals novel biological functions associated with copy number variation of large tandem repeats. PLoS Genet 10:e1004418 (2014). CHIPseq ; Human . PubMed: 24945355
  • De Vos M  et al. Poly(ADP-ribose) Polymerase 1 (PARP1) Associates with E3 Ubiquitin-Protein Ligase UHRF1 and Modulates UHRF1 Biological Functions. J Biol Chem 289:16223-16238 (2014). WB . PubMed: 24782312
  • Müller-Ott K  et al. Specificity, propagation, and memory of pericentric heterochromatin. Mol Syst Biol 10:746 (2014). ICC/IF ; Mouse . PubMed: 25134515
  • Chaudhury S  et al. FGF2 is a target and a trigger of epigenetic mechanisms associated with differences in emotionality: partnership with H3K9me3. Proc Natl Acad Sci U S A 111:11834-9 (2014). PubMed: 25071177
  • Jack AP  et al. H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization. PLoS One 8:e51765 (2013). WB . PubMed: 23451023
  • Soldi M & Bonaldi T The proteomic investigation of chromatin functional domains reveals novel synergisms among distinct heterochromatin components. Mol Cell Proteomics 12:764-80 (2013). WB . PubMed: 23319141
  • Wolf G  et al. Epigenetic marking and repression of porcine endogenous retroviruses. J Gen Virol 94:960-70 (2013). ChIP . PubMed: 23324470
  • Neguembor MV  et al. FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis. J Mol Cell Biol N/A:N/A (2013). WB, ICC/IF ; Drosophila melanogaster . PubMed: 23720823
  • Lonfat N  et al. Transgene- and locus-dependent imprinting reveals allele-specific chromosome conformations. Proc Natl Acad Sci U S A 110:11946-51 (2013). ChIP . PubMed: 23818637
  • Cruickshanks HA  et al. Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer. Nucleic Acids Res 41:6857-69 (2013). ChIP ; Mouse . PubMed: 23703216
  • Majocchi S  et al. Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes. Nucleic Acids Res N/A:N/A (2013). ChIP . PubMed: 24071586
  • Solovei I  et al. LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation. Cell 152:584-98 (2013). PubMed: 23374351
  • Oshikawa M  et al. Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner. Development 140:2310-20 (2013). IHC-Fr ; Mouse . PubMed: 23615279
  • Stender JD  et al. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell 48:28-38 (2012). WB, ChIP ; Mouse . PubMed: 22921934
  • Asensio-Juan E  et al. The histone demethylase PHF8 is essential for cytoskeleton dynamics. Nucleic Acids Res : (2012). ChIP ; Human . PubMed: 22850744
  • Wells MB  et al. Caenorhabditis elegans dosage compensation regulates histone H4 chromatin state on X chromosomes. Mol Cell Biol 32:1710-9 (2012). PubMed: 22393255
  • Driskell I  et al. The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin. EMBO J : (2011). IHC-Fr ; Mouse . PubMed: 22117221
  • Nativio R  et al. Disruption of genomic neighbourhood at the imprinted IGF2-H19 locus in Beckwith-Wiedemann syndrome and Silver-Russell syndrome. Hum Mol Genet 20:1363-74 (2011). ChIP . PubMed: 21282187
  • van Eggermond MC  et al. Epigenetic regulation of CIITA expression in human T-cells. Biochem Pharmacol : (2011). ChIP ; Human . PubMed: 21664896
  • Poleshko A  et al. Identification of a functional network of human epigenetic silencing factors. J Biol Chem 285:422-33 (2010). ChIP ; Human . PubMed: 19880521
  • Venkatarama T  et al. Repression of zygotic gene expression in the Xenopus germline. Development 137:651-60 (2010). IHC-Fr ; Xenopus laevis . PubMed: 20110330
  • Layland LE  et al. Pronounced phenotype in activated regulatory T cells during a chronic helminth infection. J Immunol 184:713-24 (2010). IHC-P ; Mouse . PubMed: 20007528
  • Wen H  et al. Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation. J Biol Chem 285:9322-6 (2010). ICC/IF ; Human . PubMed: 20129925
  • Wijeratne SS  et al. K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts. J Nutr Biochem 21:310-6 (2010). WB ; Human . PubMed: 19369050
  • Chaturvedi P & Parnaik VK Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10. PLoS One 5:e10620 (2010). WB ; Human . PubMed: 20498703
  • Liu W  et al. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature 466:508-12 (2010). WB ; Human . PubMed: 20622854
  • Kizilyaprak C  et al. In vivo chromatin organization of mouse rod photoreceptors correlates with histone modifications. PLoS One 5:e11039 (2010). Electron Microscopy ; Mouse . PubMed: 20543957
  • Carneiro T  et al. Telomeres avoid end detection by severing the checkpoint signal transduction pathway. Nature 467:228-32 (2010). ChIP ; Schizosaccharomyces pombe . PubMed: 20829797
  • Arts J  et al. JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity. Clin Cancer Res 15:6841-51 (2009). WB ; Human . PubMed: 19861438
  • Sun F  et al. Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. Mol Cancer Ther 8:3191-202 (2009). WB . PubMed: 19934278
  • Wang Y  et al. Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein. Mol Cell 33:428-37 (2009). WB ; Schizosaccharomyces pombe . PubMed: 19250904
  • Cao L  et al. A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency. Mol Cell 35:534-41 (2009). ICC/IF ; Mouse . PubMed: 19716796
  • Ciccone DN  et al. KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature 461:415-8 (2009). ICC/IF ; Mouse . PubMed: 19727073
  • Mravinac B  et al. Histone modifications within the human X centromere region. PLoS One 4:e6602 (2009). ChIP ; Human . PubMed: 19672304
  • Esnault G  et al. Transcription factor CTF1 acts as a chromatin domain boundary that shields human telomeric genes from silencing. Mol Cell Biol 29:2409-18 (2009). ChIP ; Human . PubMed: 19273604
  • Goto Y & Kimura H Inactive X chromosome-specific histone H3 modifications and CpG hypomethylation flank a chromatin boundary between an X-inactivated and an escape gene. Nucleic Acids Res 37:7416-28 (2009). ChIP . PubMed: 19843608
  • Kaneda R  et al. Genome-wide histone methylation profile for heart failure. Genes Cells 14:69-77 (2009). ChIP/Chip ; Rat . PubMed: 19077033
  • Li Y  et al. The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate. J Biol Chem 284:34283-95 (2009). PubMed: 19808676
  • Nuytten M  et al. The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing. Oncogene 27:1449-60 (2008). PubMed: 17724462
  • Donati G  et al. An NF-Y-dependent switch of positive and negative histone methyl marks on CCAAT promoters. PLoS ONE 3:e2066 (2008). ChIP ; Human . PubMed: 18446193
  • Gurtner A  et al. NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue. PLoS ONE 3:e2047 (2008). ICC/IF, ChIP ; Human, Mouse . PubMed: 18431504
  • Smith ER  et al. Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Mol Cell Biol 28:1041-6 (2008). WB ; Drosophila melanogaster . PubMed: 18039863
  • Silva L  et al. Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation. PLoS Pathog 4:e1000071 (2008). ICC/IF ; Mouse . PubMed: 18497856
  • Nicolaescu E  et al. Nature of the nuclear inclusions formed by PQBP1, a protein linked to neurodegenerative polyglutamine diseases. Eur J Cell Biol 87:817-29 (2008). PubMed: 18599155
  • Lupien M  et al. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 132:958-70 (2008). ChIP ; Human . PubMed: 18358809
  • Dunican DS  et al. xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function. Development 135:1295-302 (2008). WB . PubMed: 18305009
  • Yang H  et al. Preferential dimethylation of histone h4 lysine 20 by suv4-20. J Biol Chem 283:12085-92 (2008). WB, ICC/IF ; Drosophila melanogaster . PubMed: 18296440
  • Frye M  et al. Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. PLoS ONE 2:e763 (2007). IHC-Fr ; Mouse . PubMed: 17712411
  • Lee MG  et al. Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein. Cell 128:877-87 (2007). WB ; Human . PubMed: 17320162
  • Klose RJ  et al. The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 128:889-900 (2007). WB . PubMed: 17320163
  • Barski A  et al. High-resolution profiling of histone methylations in the human genome. Cell 129:823-37 (2007). PubMed: 17512414
  • Tan J  et al. Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev 21:1050-63 (2007). WB ; Human . PubMed: 17437993
  • Sautel CF  et al. SET8-mediated methylations of histone H4 lysine 20 mark silent heterochromatic domains in apicomplexan genomes. Mol Cell Biol 27:5711-24 (2007). WB ; Toxoplasma gondii . PubMed: 17562855
  • Luciani JJ  et al. PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase. J Cell Sci 119:2518-31 (2006). PubMed: 16735446
  • Kimura H  et al. A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B. J Cell Biol 175:389-400 (2006). PubMed: 17074886
  • Houlard M  et al. CAF-1 is essential for heterochromatin organization in pluripotent embryonic cells. PLoS Genet 2:e181 (2006). PubMed: 17083276
  • Brusa G  et al. P210 Bcr-abl tyrosine kinase interaction with histone deacetylase 1 modifies histone H4 acetylation and chromatin structure of chronic myeloid leukaemia haematopoietic progenitors. Br J Haematol 132:359-69 (2006). PubMed: 16409301
  • Mayer C  et al. Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol Cell 22:351-61 (2006). PubMed: 16678107
  • Talasz H  et al. Histone H4-lysine 20 monomethylation is increased in promoter and coding regions of active genes and correlates with hyperacetylation. J Biol Chem 280:38814-22 (2005). PubMed: 16166085
  • Sanders SL  et al. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 119:603-14 (2004). PubMed: 15550243
  • Chadwick BP & Willard HF Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. Proc Natl Acad Sci U S A : (2004). PubMed: 15574503
  • Sanders SL  et al. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 119:603-14 (2004). PubMed: 15550243
  • Sarg B  et al. Histone H4 hyperacetylation precludes histone H4 lysine 20 trimethylation. J Biol Chem 279:53458-64 (2004). PubMed: 15456746
  • Biron VL  et al. Distinct dynamics and distribution of histone methyl-lysine derivatives in mouse development. Dev Biol 276:337-51 (2004). PubMed: 15581869

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