Overview

  • Product nameAnti-HIV gp160 antibody
  • Description
    Goat polyclonal to HIV gp160
  • Specificityab117122 reacts strongly with gp41, gp120 and gp160 in western blot assays. ELISA based peptide mapping studies have confirmed high titer reactivity to HIV MN env peptide in the following regions: (6332)IEPLGVAPTKAKRRV, (6360) CTTTVPWNASWSNKS and moderate activity to multiple other regions on the env polypeptide.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Immunogen

    Other Immunogen Type corresponding to HIV gp160. ab117122 was produced using a cocktail of three recombinant antigens: gp41, gp120, and gp41/120 hybrid.

Properties

Applications

Our Abpromise guarantee covers the use of ab117122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 97 kDa.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceEndoproteolytic processing of human immunodeficiency virus type 1 (HIV1) gp160 membrane glycoprotein precursor into gp120 and gp41 is necessary for formation of infectious HIV particles. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
  • Cellular localizationCell Membrane
  • Alternative names
    • env antibody
    • Env polyprotein antibody
    • Envelope glycoprotein gp160 antibody
    • Glycoprotein 120 antibody
    • Glycoprotein 41 antibody
    • SU antibody
    • Surface protein antibody
    • Transmembrane protein gp41 antibody
    see all

References for Anti-HIV gp160 antibody (ab117122)

ab117122 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Human Cell lysate - whole cell (HEK293T cells)
Gel Running Conditions Reduced Denaturing (4-12)
Loading amount 10 µg
Treatment Transfected with HIV-1 NL4-3 for 48 hours
Specification HEK293T cells
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 25°C
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Submitted Aug 24 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"