Anti-HIV1 gp120 antibody (Biotin) (ab20105)

Overview

  • Product nameAnti-HIV1 gp120 antibody (Biotin)
    See all HIV1 gp120 primary antibodies
  • Description
    Goat polyclonal to HIV1 gp120 (Biotin)
  • ConjugationBiotin
  • SpecificityThis antibody is specific for gp120. Antiserum does not cross-react with human T or B cells. It is not reactive with human or bovine sera.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
  • Immunogen

    Purified native gp120 from strain IIIB.

  • General notes

    Covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution.

Properties

Applications

Our Abpromise guarantee covers the use of ab20105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 120 kDa. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceHIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
    • Cellular localizationEnvelope surface glycoprotein.
    • Alternative names
      • Glycoprotein 120 antibody
      • gp120 antibody
      • SU antibody
      • Surface protein antibody

    References for Anti-HIV1 gp120 antibody (Biotin) (ab20105)

    ab20105 has not yet been referenced specifically in any publications.

    Product Wall

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    Thank you for your enquiry. I have been in touch with the source of these HIV gp120 and gp41 antibodies and I have determine that unfortunately none of them have been tested against the HIV strain YU2. I can tell you that ab18633 is predicted, base...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"