Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab49059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityDetects many HIV-type O infected individuals responding to HIV envelope antibodies.
  • Applications

    ELISA

    Western blot

  • FormLiquid
  • Additional notesDetects many HIV-type O infected individuals responding to HIV envelope antibodies.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names
    • Glycoprotein 120
    • Glycoprotein 41
    • HIV1 gp120
    • HIV1 gp41
    • SU
    • TM
    see all
  • Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

References for HIV1 gp120 + gp41 peptide (ab49059)

ab49059 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"