The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
Glycoprotein 41 antibody
Human Immunodeficiency Virus 1 antibody
Transmembrane protein antibody
References for Anti-HIV1 gp41 antibody [1D4] (ab18633)
has not yet been referenced specifically in any publications.
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