Overview

  • Product nameAnti-HIV1 gp41 antibody
    See all HIV1 gp41 primary antibodies
  • Description
    Goat polyclonal to HIV1 gp41
  • SpecificityAb20890 detects Human Immunodeficiency Virus Type 1 (HIV-1), gp41: amino acid 546-682 sequence from strain HxB2. The antiserum does not cross-react with human T or B cells. Antiserum has not been absorbed to remove anti-beta-galactosidase activity. We have data to indicate that this antibody may not cross react with Human. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • Tested applicationsSuitable for: WBmore details
  • Immunogen

    Recombinant (P. Pastoris) ectodomain of gp41 (glycosylated)

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesAb20890 is purified by sodium sulfate precipitation and ion-exchange chromatography. The antiserum has not been adsorbed to remove anti-beta-galactosidase activity.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab20890 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100. Predicted molecular weight: 41 kDa. Major band seen in WB at 41kDa and a minor band at 20kDa. Dilution optimised using Chromogenic detection.

Target

  • Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
  • Alternative names
    • Env antibody
    • Glycoprotein 41 antibody
    • gp41 antibody
    • Human Immunodeficiency Virus 1 antibody
    • TM antibody
    • Transmembrane protein antibody
    see all

References for Anti-HIV1 gp41 antibody (ab20890)

ab20890 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I have been in touch with the source of these HIV gp120 and gp41 antibodies and I have determine that unfortunately none of them have been tested against the HIV strain YU2. I can tell you that ab18633 is predicted, base...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"