Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab68129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab68129 is immunoreactive with all sera of HIV1 infected individuals.
  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Purity> 90 % by SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 8M Urea, 20mM PBS, 20mM Sodium chloride, 1mM DTT, pH 7.8

General info

  • Alternative names
    • Env
    • Env polyprotein
    • Envelope glycoprotein gp160
    • Envelope Protein gp120
    • Glycoprotein 41
    • GP120
    • gp41
    • Human Immunodeficiency Virus 1
    • Human Immunodeficiency Virus Type 1 gp41
    • TM
    • Transmembrane protein
    see all
  • Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

References for HIV1 gp41 full length protein (ab68129)

This product has been referenced in:
  • Eissmann K  et al. HIV-1 fusion is blocked through binding of GB Virus C E2D peptides to the HIV-1 gp41 disulfide loop. PLoS One 8:e54452 (2013). ELISA . Read more (PubMed: 23349893) »

See 1 Publication for this product

Product Wall

Abreviews
Application Functional Studies
This recombinnat protein was used to stimulated human PBMCs and cytokines were determined.
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Verified customer

Submitted Sep 03 2013

Thank you for contacting Abcam.

I have heard back from the lab about ab68129 and I received the following product description: "ab68129 is a non-glycosylated 288 amino acids polypeptide chain (a.a. 466-753) having a molecular mass of 32k...

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Unfortunately, the information you asked for is considered as proprietary know-how.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"