Overview

  • Product name
    Anti-HIV1 p24 antibody [38/8.7.47]
    See all HIV1 p24 primary antibodies
  • Description
    Mouse monoclonal [38/8.7.47] to HIV1 p24
  • Specificity
    This murine monoclonal antibody reacts with Human Immunodeficiency Virus Type 1(HIV 1) p24 protein.
  • Tested applications
    Suitable for: Radioimmunoprecipitation, WB, ELISA, ICC/IFmore details
  • General notes

    The antibody is used to detect HIV-1 core protein in virus infected cells as well as in viral or infected cell lysates. Studies on core antigen synthesis and metabolism can be performed using Western blotting or radioimmunoprecipitation analysis.

    Antibody dilutions should be prepared using buffers containing suitable protein in order to stabilize antibody activity.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Phosphate buffered saline
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    Purified from serum-free culture supernatant.
  • Primary antibody notes
    The antibody is used to detect HIV-1 core protein in virus infected cells as well as in viral or infected cell lysates. Studies on core antigen synthesis and metabolism can be performed using Western blotting or radioimmunoprecipitation analysis.
  • Clonality
    Monoclonal
  • Clone number
    38/8.7.47
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab9044 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Radioimmunoprecipitation Use at an assay dependent dilution.
WB Use a concentration of 1 - 10 µg/ml.
ELISA Use at an assay dependent dilution.
ICC/IF Use a concentration of 1 - 10 µg/ml.

Target

  • Relevance
    HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.
  • Cellular localization
    Membrane
  • Alternative names
    • CA antibody
    • Capsid protein p24 antibody
    • HIV-1 Gag p24 antibody
    • HIV1gp1 antibody
    • Human immunodeficiency virus 1 antibody
    • Human immunodeficiency virus type 1 p24 antibody
    see all

Anti-HIV1 p24 antibody [38/8.7.47] images

  • The images shows HIVADA-infected PBMC in vitro stained with ab9044. These images were kindly supplied as part of the review submitted by Eliseo Eugenin.

References for Anti-HIV1 p24 antibody [38/8.7.47] (ab9044)

This product has been referenced in:
  • Reiser K  et al. The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition. PLoS One 11:e0147773 (2016). Read more (PubMed: 26816344) »
  • Wasilewski LN  et al. A Hepatitis C Virus Envelope Polymorphism Confers Resistance to Neutralization by Polyclonal Sera and Broadly Neutralizing Monoclonal Antibodies. J Virol 90:3773-82 (2016). Read more (PubMed: 26819308) »

See all 9 Publications for this product

Product Wall

Thank you for bringing to my attention the HIV1 p24 antibody ab113659. This antibody has in fact been tested in flow cytometry. Since it has been tested for flow cytometry and is known to work, it is covered by our guarantee: replacement or refund of a...

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Thank you for your enquiry. I have enquired at the originator of the product for the epitope sequence but unfortunately, they have not done mapping on this antibody. I am sorry I can't be of more assistance in this occasion. Should you require an...

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This antibody will recognise p55 as well as p24. We are not aware of an antibody that will only recognise p24.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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