Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab43015 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
Flow Cyt
  • Application notes
    ELISA: 1/500. Use Streptavidin (HRP) conjugated detection reagent.
    Flow Cyt: 1/200. Use Streptavidin-FITC conjugated detection reagent.
    WB: 1/1000. Predicted molecular weight: 14 kDa. Use Streptavidin (HRP) conjugated detection reagent.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
    • Cellular localization
      Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
    • Alternative names
      • p14 antibody
      • Protein Tat antibody
      • Transactivating regulatory protein antibody

    References

    This product has been referenced in:
    • Johnson TP  et al. Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein. Proc Natl Acad Sci U S A 110:13588-93 (2013). Read more (PubMed: 23898208) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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