Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab83353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum.
  • Applications

    Blocking

    Western blot

    SDS-PAGE

  • Purity> 90 % by SDS-PAGE.

  • FormLyophilised
  • Additional Notesab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Store at -70°C

    Preservative: None
    Constituents: 0.1% Glycerol

  • ReconstitutionThe protein should be reconstituted in apirogenic sterile water or PBS buffer. The reconstituted solution has to be used immediately.

General info

  • Alternative names
    • p14
    • Protein Tat
    • Transactivating regulatory protein
  • RelevanceHIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
  • Cellular localizationNuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.

References for HIV1 tat full length protein (ab83353)

This product has been referenced in:
  • Qu J  et al. The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10. BMC Immunol 13:15 (2012). Read more (PubMed: 22471703) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"