Anti-HIV2 gp36 antibody [3B10/G2] (ab18628)
Key features and details
- Mouse monoclonal [3B10/G2] to HIV2 gp36
- Suitable for: ELISA, WB
- Reacts with: HIV-2
- Isotype: IgG2a
Overview
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Product name
Anti-HIV2 gp36 antibody [3B10/G2] -
Description
Mouse monoclonal [3B10/G2] to HIV2 gp36 -
Host species
Mouse -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: HIV-2 -
Immunogen
HIV2 recombinant antigen 00114-V.
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Epitope
Recognition epitope resides between amino acid residues 390a.a.-702 a.a. of HIV gp36 antigen. -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
3B10/G2 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab18628 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
1/500.
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WB |
1/1000. Predicted molecular weight: 34 kDa.
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Notes |
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ELISA
1/500. |
WB
1/1000. Predicted molecular weight: 34 kDa. |
Target
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Relevance
HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. Little is known about the best approach to the clinical treatment and care of patients infected with HIV2. Some drugs used to treat HIV1 are ineffective. HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response. Hence, most licensed diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific antibodies. It is becoming important to differentiate between single infection with either HIV1 or HIV2 and dual infection. -
Alternative names
- Gp36 antibody
- HIV 2 antibody
- Human immunodeficiency virus 2 antibody
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab18628 has not yet been referenced specifically in any publications.