Overview

  • Product nameAnti-HIV2 Nef antibody [4B5]
  • Description
    Rat monoclonal [4B5] to HIV2 Nef
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with HIV2. It does not react with HIV1. Not yet tested in other species.
  • Immunogen

    Fusion protein: TrpE-Fusion protein

Properties

Applications

Our Abpromise guarantee covers the use of ab22626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 35 kDa.
IP Use at an assay dependent dilution.

Target

  • RelevanceNef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
  • Cellular localizationCell Membrane
  • Alternative names
    • F-protein antibody
    • HIV2 nef protein antibody
    • Human immunodeficiency virus 2 nef antibody
    • Nef protein antibody
    • Negative factor antibody
    see all

References for Anti-HIV2 Nef antibody [4B5] (ab22626)

ab22626 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"