The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Predicted molecular weight: 35 kDa.
Use at an assay dependent dilution.
RelevanceNef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
Cellular localizationCell Membrane
HIV2 nef protein antibody
Human immunodeficiency virus 2 nef antibody
Nef protein antibody
Negative factor antibody
References for Anti-HIV2 Nef antibody [4B5] (ab22626)
has not yet been referenced specifically in any publications.
Publishing research using ab22626? Please let us know so that we can cite the reference in this datasheet.
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